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An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets [ferret]

(Submitter supplied) Influenza A viruses (IAVs) present major public health threats from annual seasonal epidemics and pandemics as well as from viruses adapted to a variety of animals including poultry, pigs, and horses. Vaccines that broadly protect against all such IAVs, so-called “universal” influenza vaccines, do not currently exist, but are urgently needed. Here, we demonstrated that an inactivated, multivalent whole virus vaccine, delivered intramuscularly or intranasally, was broadly protective against challenges with multiple IAV hemagglutinin and neuraminidase subtypes in both mice and ferrets. more...
Organism:
Mustela putorius furo
Type:
Expression profiling by array
Platform:
GPL32337
40 Samples
Download data: TXT
Series
Accession:
GSE205840
ID:
200205840

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