GEO DataSet Links for BioProject (Select 91459) - GEO DataSets

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Items: 2

Select item 2000022751.

A Bioinformatic Analysis of Arginine-Sensitive Regulation of rat Hepatic Gene Expression

(Submitter supplied) Goals of the Study: 1. Assess the scope of arginine-responsive hepatic gene expression using in vitro rat models. 2. Compare normal and tumorigenic cells 3. Identify potentially novel genes and pathways that may be subject to amino acid (arginine) regulation Background: We previously reported that mRNA levels of the tumor associated glycoprotein amino acid transporter TA1/LAT1/ CD98 light chain arginine increase in normal hepatic cells under low arginine conditions while levels are constitutive and high in hepatic tumor cells. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1622
Platform:: GPL1355
12 Samples

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Accession:: GSE2275

ID:: 200002275

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Select item 16222.

Arginine deprivation effect on tumorigenic hepatic cells

Analysis of neoplastic hepatic cells subjected to arginine deprivation. Results identify arginine responsive genes that become unresponsive to arginine in tumorigenic cells.