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Multiple parallel cell lineages in the developing mammalian cerebral cortex

(Submitter supplied) Cortical neurogenesis follows a simple lineage: apical Radial Glia Cells (RGC) generate basal progenitors, and these produce neurons. How this occurs in species with expanded germinal zones and a folded cortex, like human, remains unclear. We used single-cell RNA sequencing from individual cortical germinal zones in ferret, and barcoded lineage tracking, to determine the molecular diversity of progenitor cells and their lineages. more...
Organism:
Mustela putorius; Mustela putorius furo
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL28629 GPL32908
26 Samples
Download data: MTX, TSV
Series
Accession:
GSE234305
ID:
200234305

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