Similar studies for GEO DataSets (Select 1095) - GEO DataSets

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Items: 20

Select item 10951.

Hematopoeitic stem cells of various types

Expression profiling of Lin-CD34-, Lin-CD34+, and Lin+CD34+ peripheral blood hematopoeitic stem cells (HSCs). Results provide insight into the molecular basis of the association of CD34 expression with self-renewal and lineage commitment in HSCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 cell type sets

Platform:: GPL8300
Series:: GSE1493
6 Samples

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DataSet

Accession:: GDS1095

ID:: 1095

Select item 2000014932.

Hematopoietic stem cell subsets

(Submitter supplied) Hematopoietic stem cell (HSC) subsets based on the CD34 expression and/or lineage markers expression Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1095
Platform:: GPL8300
6 Samples

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Series

Accession:: GSE1493

ID:: 200001493

Select item 2000037883.

Lin-, CD38-, CD34+ Hematopoietic Stem Cells.

(Submitter supplied) Lin-, CD38-, CD34+ hematopoietic stem cells. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL97 GPL96
6 Samples

Download data: CEL, EXP

Series

Accession:: GSE3788

ID:: 200003788

Select item 2000080404.

CD34 antigen role in haematopoietic commitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE8040

ID:: 200008040

Select item 2000080035.

CD34 Overexpression

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we overexpressed the human CD34 cDNA in human CD34+ cells by retroviral gene transfer. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8003

ID:: 200008003

Select item 2000080026.

CD34 gene silencing

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we silenced the CD34 gene expression in CD34+ stem/progenitor cells using a siRNA approach. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8002

ID:: 200008002

Select item 2000046887.

Molecular phenotype of G-CSF- or pegylated G-CSF-mobilized CD34+ cells

(Submitter supplied) Peripheral blood stem and progenitor cells (PBSC) are widely used for autologous and allogeneic hematopoietic stem cell transplantation. PBSC can be mobilized into the peripheral blood using cytokines, cytotoxic chemotherapy or a combination of both. Granulocyte colony stimulating factor (G-CSF) has become the most commonly administered cytokine for PBSC mobilization because of its high potency and lack of serious toxicity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2321
Platform:: GPL201
16 Samples

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Series

Accession:: GSE4688

ID:: 200004688

Select item 23218.

Polyethylene glycol-conjugated G-CSF mobilized CD34+ cells

Analysis of granulocyte colony stimulating factor (G-CSF) or polyethylene glycol-conjugated (pegylated) G-CSF mobilized CD34+ hematopoietic stem and progenitor cells from multiple myeloma patients undergoing chemotherapy. Pegylated G-CSF has a longer half-life than unconjugated G-CSF.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL201
Series:: GSE4688
16 Samples

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DataSet

Accession:: GDS2321

ID:: 2321

Select item 2000030039.

Gene expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix

(Submitter supplied) CD34+ hematopoietic stem/progenitor cells (HSC) reside in the bone marrow in close vicinity to the endosteal bone surface, surrounded by osteoblasts, stromal cells and various extracellular matrix molecules. We utilized a bioartificial matrix containing fibrillar collagen I, the major matrix component of bone, as scaffold for ex vivo expansion of HSCs. CD34+ HSCs were isolated from umbilical cord blood and cultivated within reconstituted collagen I fibrils in presence of FLT3-ligand, SCF and IL-3. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1401
Platform:: GPL96
6 Samples

Download data

Series

Accession:: GSE3003

ID:: 200003003

Select item 140110.

CD34+ hematopoietic cells expanded in artificial matrix of fibrillar collagen I

Analysis of CD34+ hematopoietic stem/progenitor cells (HSC) expanded for 7 days in an artificial matrix of fibrillar collagen I, the major matrix component of bone. Results provide insight into the limitations of ex vivo expansion to increase the number of transplantable HSCs from cord blood.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL96
Series:: GSE3003
6 Samples

Download data

DataSet

Accession:: GDS1401

ID:: 1401

Select item 20000341011.

IM CD34+ progenitors cells

(Submitter supplied) IM CD34+ vs BM CD34+ cells Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2397
Platform:: GPL96
6 Samples

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Series

Accession:: GSE3410

ID:: 200003410

Select item 239712.

Idiopathic myelofibrosis: hematopoietic CD34+ stem cells

Analysis of pooled hematopoietic CD34+ stem cells from peripheral blood of patients with idiopathic myelofibrosis (IM), a rare chronic myeloproliferative disorder. Results provide insight into the molecular pathogenesis of IM.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE3410
6 Samples

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DataSet

Accession:: GDS2397

ID:: 2397

Select item 20001604213.

Retroviral transduction of CD34+ cells with P190 and P210 BCR/ABL1 fusion genes

(Submitter supplied) Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage The P190 and P210 BCR/ABL1 fusion genes are mainly associated with different types of hematologic malignancies, but it is presently unclear whether they are functionally different following expression in primitive human hematopoietic cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL5886
18 Samples

Download data: GPR

Series

Accession:: GSE16042

ID:: 200016042

Select item 20003128314.

Expression data from untreated and valproic acid (VPA) treated CD34+ Hematopoietic Stem Cells (HSCs)

(Submitter supplied) Histone deacetylase (HDAC) inhibitors are widely utilized in hematopoietic malignance therapy; nevertheless, little is currently known concerning their effects on normal myelopoiesis. In order to investigate a putative interference of HDAC inhibitors in myeloid commitment of hematopoietic stem/progenitor cells (HSPCs) we treated CD34+ cells with valproic acid (VPA). Moreover, we investigate changes in gene expression induced by VPA treatment on HSPCs, by means of microarray analysis in VPA treated and untreated (CTR) CD34+ cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
2 Samples

Download data: CEL, CHP

Series

Accession:: GSE31283

ID:: 200031283

Select item 20000202615.

Global transcription analysis of immature avian erythrocytic progenitors

(Submitter supplied) The molecular mechanisms regulating the cell fate decision between self-renewal and differentiation/apoptosis in stem and progenitor cells are poorly understood. Here, we report the first comprehensive identification of genes potentially involved in the switch from self-renewal toward differentiation of primary, non-immortalized erythroid avian progenitor cells (T2EC cells). We used the Serial Analysis of Gene Expression (SAGE) technique in order to identify and quantify the genome fraction functionally active in a self-renewing versus a differentiating cell population. more...

Organism:: Gallus gallus

Type:: Expression profiling by SAGE

Platform:: GPL1724
2 Samples

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Series

Accession:: GSE2026

ID:: 200002026

PubMed Similar studies

Select item 20001947116.

Gene epression profile in human BM-MSC

(Submitter supplied) Gene expression profiles of human BM-MSC isolated form normal donor to elucidate potential molecular network for clinical application

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
4 Samples

Download data: CEL

Series

Accession:: GSE19471

ID:: 200019471

Select item 20000180117.

Human hematopoietic stem cell engraftment in goat

(Submitter supplied) Robust human-goat chimerism was achieved by transplanting human CD34+Lin- cord blood cells into fetal goats. We observed a broad distribution of GFP-marked human cells in non-hematopoietic organs including kidney, muscle, lung, and heart of transplant goats. Various marker techniques indicated that human genes were expressed in chimeric livers and blood. Keywords: other

Organism:: Homo sapiens; Capra hircus

Type:: Expression profiling by array

Dataset:: GDS1023
Platform:: GPL96
23 Samples

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Series

Accession:: GSE1801

ID:: 200001801

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 102318.

Hematopoietic stem cell engraftment in goat

Human-goat chimerism achieved by transplanting human CD34+Lin- cord blood cells into fetal goats. Markers indicate human genes expressed in goat liver and blood. Human/goat hematopoietic stem cell (HSC) xenogeneic model allows analysis of HSC transplantation, expansion and differentiation in vivo.

Organism:: Homo sapiens; Capra hircus

Type:: Expression profiling by array, count, 2 protocol, 2 species, 2 tissue sets

Platform:: GPL96
Series:: GSE1801
23 Samples

Download data

DataSet

Accession:: GDS1023

ID:: 1023

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20003404419.

Gene expression profiles of AML derived stem cells: similarity to hematopoietic stem cells

(Submitter supplied) Tumors contain a fraction of cancer stem cells that maintain the propagation of the disease. The CD34‏CD38_ cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic stem cells (LSC). We isolated the CD34‏CD38_ cell fraction from AML and compared their gene expression profiles to the CD34‏CD38‏ cell fraction, using microarrays. We found 409 genes that were at least twofold over- or underexpressed between the two cell populations. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4301
Platform:: GPL571
8 Samples

Download data: CEL

Series

Accession:: GSE34044

ID:: 200034044

Select item 430120.

Acute myeloid leukemia CD34+CD38- cell population

Analysis of CD34+CD38- and CD34+CD38+ cell fractions isolated from 5 acute myeloid leukemia (AML) patients. AML CD34+CD38- cells are enriched leukemic stem cells (LSC) that maintain the propagation of the disease. Results provide insight into molecular mechanisms that maintain and characterize LSC.