Similar studies for GEO DataSets (Select 177) - GEO DataSets

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Items: 2

Select item 1771.

Cytomegalovirus strain comparison

Human foreskin fibroblasts (HFF) infected with cytomegalovirus strains fhCMV-H (rapid spread in vitro) and fhCMV-T (slow spread in vitro). UV-inactivated viruses also examined to control for response to coat glycoprotein B and active viral infection.

Organism:: Homo sapiens

Type:: Expression profiling by array, log ratio, 2 protocol, 3 strain sets

Platform:: GPL44
Series:: GSE453
16 Samples

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Accession:: GDS177

ID:: 177

Select item 2000004532.

fhCMV-H vs fhCMV-T

(Submitter supplied) Cytomegalovirus (CMV) strains with different in vivo and in vitro characteristics may induce different patterns of cellular gene expression. CMV strain fhCMV-H, which spreads rapidly through cell culture, was isolated from a hematopoetic stem cell transplant patient who died of CMV-mediated marrow failure. In contrast fhCMV-T was isolated from a patient who survived CMV complications and does not spread rapidly in vitro. more...