Similar studies for GEO DataSets (Select 200003410) - GEO DataSets

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Items: 20

Select item 2000034101.

IM CD34+ progenitors cells

(Submitter supplied) IM CD34+ vs BM CD34+ cells Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2397
Platform:: GPL96
6 Samples

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Series

Accession:: GSE3410

ID:: 200003410

Select item 23972.

Idiopathic myelofibrosis: hematopoietic CD34+ stem cells

Analysis of pooled hematopoietic CD34+ stem cells from peripheral blood of patients with idiopathic myelofibrosis (IM), a rare chronic myeloproliferative disorder. Results provide insight into the molecular pathogenesis of IM.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE3410
6 Samples

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DataSet

Accession:: GDS2397

ID:: 2397

Select item 2000037883.

Lin-, CD38-, CD34+ Hematopoietic Stem Cells.

(Submitter supplied) Lin-, CD38-, CD34+ hematopoietic stem cells. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL96 GPL97
6 Samples

Download data: CEL, EXP

Series

Accession:: GSE3788

ID:: 200003788

Select item 2000046884.

Molecular phenotype of G-CSF- or pegylated G-CSF-mobilized CD34+ cells

(Submitter supplied) Peripheral blood stem and progenitor cells (PBSC) are widely used for autologous and allogeneic hematopoietic stem cell transplantation. PBSC can be mobilized into the peripheral blood using cytokines, cytotoxic chemotherapy or a combination of both. Granulocyte colony stimulating factor (G-CSF) has become the most commonly administered cytokine for PBSC mobilization because of its high potency and lack of serious toxicity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2321
Platform:: GPL201
16 Samples

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Series

Accession:: GSE4688

ID:: 200004688

Select item 23215.

Polyethylene glycol-conjugated G-CSF mobilized CD34+ cells

Analysis of granulocyte colony stimulating factor (G-CSF) or polyethylene glycol-conjugated (pegylated) G-CSF mobilized CD34+ hematopoietic stem and progenitor cells from multiple myeloma patients undergoing chemotherapy. Pegylated G-CSF has a longer half-life than unconjugated G-CSF.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL201
Series:: GSE4688
16 Samples

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DataSet

Accession:: GDS2321

ID:: 2321

Select item 2000014936.

Hematopoietic stem cell subsets

(Submitter supplied) Hematopoietic stem cell (HSC) subsets based on the CD34 expression and/or lineage markers expression Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1095
Platform:: GPL8300
6 Samples

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Series

Accession:: GSE1493

ID:: 200001493

Select item 10957.

Hematopoeitic stem cells of various types

Expression profiling of Lin-CD34-, Lin-CD34+, and Lin+CD34+ peripheral blood hematopoeitic stem cells (HSCs). Results provide insight into the molecular basis of the association of CD34 expression with self-renewal and lineage commitment in HSCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 cell type sets

Platform:: GPL8300
Series:: GSE1493
6 Samples

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DataSet

Accession:: GDS1095

ID:: 1095

Select item 2000030038.

Gene expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix

(Submitter supplied) CD34+ hematopoietic stem/progenitor cells (HSC) reside in the bone marrow in close vicinity to the endosteal bone surface, surrounded by osteoblasts, stromal cells and various extracellular matrix molecules. We utilized a bioartificial matrix containing fibrillar collagen I, the major matrix component of bone, as scaffold for ex vivo expansion of HSCs. CD34+ HSCs were isolated from umbilical cord blood and cultivated within reconstituted collagen I fibrils in presence of FLT3-ligand, SCF and IL-3. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1401
Platform:: GPL96
6 Samples

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Series

Accession:: GSE3003

ID:: 200003003

Select item 14019.

CD34+ hematopoietic cells expanded in artificial matrix of fibrillar collagen I

Analysis of CD34+ hematopoietic stem/progenitor cells (HSC) expanded for 7 days in an artificial matrix of fibrillar collagen I, the major matrix component of bone. Results provide insight into the limitations of ex vivo expansion to increase the number of transplantable HSCs from cord blood.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL96
Series:: GSE3003
6 Samples

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DataSet

Accession:: GDS1401

ID:: 1401

Select item 20001288610.

Effect of the silencing of WT1 expression on HCC transcriptome

(Submitter supplied) The Wilms´ tumor 1 gene (WT1) encodes a transcription factor involved in cell growth and development. As we previously reported WT1 expression is hardly detectable in normal hepatic tissue but is induced in liver cirrhosis. Although WT1 has been found to be overexpressed in a number of malignancies, the role of WT1 in hepatocarcinogenesis has not been clarified. We found that WT1 is expressed in several human hepatocellular carcinoma (HCC) cell lines including PLC/PRF/5 and HepG2, and in HCC tumor tissue in 42% of patients. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE12886

ID:: 200012886

Select item 20002604911.

Expression data from patients with Essentiel Thrombocythemia (ET), Polycythemia Vera (PV), Primary Myelofibrosis (PMF) and control subjects

(Submitter supplied) We used microarrays to assess gene expression in patients with ET, PV, and PMF compared to control subjects

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
181 Samples

Download data: CEL

Series

Accession:: GSE26049

ID:: 200026049

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000804012.

CD34 antigen role in haematopoietic commitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE8040

ID:: 200008040

Select item 20000800313.

CD34 Overexpression

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we overexpressed the human CD34 cDNA in human CD34+ cells by retroviral gene transfer. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8003

ID:: 200008003

Select item 20000800214.

CD34 gene silencing

(Submitter supplied) In order to investigate the role of CD34 antigen in haematopoietic commitment, we silenced the CD34 gene expression in CD34+ stem/progenitor cells using a siRNA approach. Keywords: treatment comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
3 Samples

Download data: CEL

Series

Accession:: GSE8002

ID:: 200008002

Select item 20001052515.

Gene expression profile of Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP)

(Submitter supplied) Gene expression profile of Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) reveals murine targets for preclinical development of human prostate cancer therapy In this study, we have generated an open source TRAMP microarray dataset to identify differentially expressed genes from human prostate cancer that have concordant expression in TRAMP tumors, and thereby represent lead targets for preclinical therapy development. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
18 Samples

Download data: CEL

Series

Accession:: GSE10525

ID:: 200010525

Select item 20000891416.

CHRF-288-11 and primary human megakaryocytic cell cultures provide novel insights into lineage-specific differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2926
Platform:: GPL887
77 Samples

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Series

Accession:: GSE8914

ID:: 200008914

Select item 20000383917.

Temporal expression profile of megakaryocytic differentiation primary CD34+ cell culture

(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of Mk differentiation human CD34-positive hematopoietic stem and progenitor cells cultured with thrombopoietin, interleukin-3, and Flt3-ligand. The goal this study was to identify genes involved in the various facets of Mk differentiation including commitment, polyploidization, proplatelet formation, and apoptosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
36 Samples

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Series

Accession:: GSE3839

ID:: 200003839

Select item 20000383818.

Temporal expression profile of CHRF-288 cell line after phorbol ester stimulation

(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of phorbol-ester-induced Mk differentiation of the megakaryoblastic CHRF-288-11 (CHRF) cell line – a model system for investigating megakaryopoiesis. The goals of this study were to (1) verify the megakaryocytic nature of the CHRF cell line at the transcriptional level, and (2) extract novel insights into the key facets of Mk maturation including polyploidization, proplatelet formation, and apoptosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
41 Samples

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Series

Accession:: GSE3838

ID:: 200003838

Select item 292619.

Megakaryocytic differentiation: time course

Temporal analysis of phorbol ester-treated CHRF-288-11 megakaryoblastic cells induced to undergo megakaryocytic (Mk) differentiation and primary Mk (PriMk) cells derived from cytokine-treated CD34+ peripheral blood cells. Results provide insight into molecular mechanisms underlying megakaryopoiesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, log e ratio, 4 agent, 2 cell line, 13 time sets

Platform:: GPL887
Series:: GSE8914
77 Samples

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DataSet

Accession:: GDS2926

ID:: 2926

Select item 20006908920.

Short RNAs expression profiling in circulating CD34+ cells from Primary Myelofibrosis patients and from normal controls pooled bone marrow CD34+ cells.

(Submitter supplied) We report the application of Illumina short RNA sequencing for characterization and discovery of miRNAs and moRNAs, and for identification of differentially expressed small RNAs in circulating CD34+ cells from Primary Myelofibrosis (PMF) patients and from normal controls pooled bone marrow CD34+ cells.