Similar studies for GEO DataSets (Select 200006877) - GEO DataSets

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Items: 4

Select item 2000068771.

SREBP1c and mock virus expression profiles in AG01518 human fibroblasts

(Submitter supplied) Sterol-regulatory element binding proteins (SREBP) control the expression of most genes involved in fatty acid and cholesterol metabolism. In this report, using microarrays, we showed that SREBP1 also induced genes unrelated to lipid biosynthesis, such as heme oxygenase 1 (HMOX1), the phosphatidylinositol-3 kinase regulatory subunit p55-gamma, synaptic vesicle glycoprotein 2A (SV2A) and COTE1 (C1orf2). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL506
3 Samples

Download data: TXT

Series

Accession:: GSE6877

ID:: 200006877

Select item 2000014842.

PDGF stimulation kinetics

(Submitter supplied) Subconfluent AG01518 fibroblasts were starved for 16 hours in the presence of 0.1% BSA, and then stimulated for 1, 4, 10 or 24 hours with PDGF-BB (10 ng/ml in starvation medium), or left untreated for the same periods of time. Total RNA was isolated using the RNeasy kit (Qiagen). The RNA quality was checked by formaldehyde agarose gel electrophoresis (RNeasy protocol, Qiagen). Total RNA (40 mg) from cells treated for a given period of time with PDGF or starvation medium alone were labelled in reverse transcription reactions (Superscript II kit, Invitrogen) with dCTP-Cy5 and dCTP-Cy3, respectively (Amersham). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1768
Platform:: GPL506
18 Samples

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Series

Accession:: GSE1484

ID:: 200001484

Select item 17683.

Platelet-derived growth factor effect on fibroblasts: time course

Expression profiling of AG01518 foreskin fibroblasts at various time points up to 24 hours following stimulation with 10 ng/ml platelet-derived growth factor (PDGF). PDGF is a potent mitogen for fibroblasts and other cells of mesenchymal origin. Results identify genes regulated by PDGF.

Organism:: Homo sapiens

Type:: Expression profiling by array, log2 ratio, 4 time sets

Platform:: GPL506
Series:: GSE1484
18 Samples

Download data

DataSet

Accession:: GDS1768

ID:: 1768

Select item 2000109184.

Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways.

(Submitter supplied) In this study we have identified the target genes of SREBP1a and SREBP1c in primary cultures of human skeletal muscle cells using adenoviral vectors expressing the mature nuclear form of human SREBP1a or SREBP1c combined with oligonucleotide microarrays. Keywords: comparison of human myotubes infected either by SREBP1a or 1C