Similar studies for GEO DataSets (Select 200019314) - GEO DataSets

Links from GEO DataSets

Items: 20

Select item 2000193141.

Sarcoidosis-specific markers from whole blood gene expression

(Submitter supplied) We hypothesized that microarray analyses of whole blood gene expression would identify patterns of gene expression useful in the diagnosis for sacroidosis and identify inflammatory mediators relevant to the underlying pathophysiology.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4587
Platform:: GPL570
66 Samples

Download data: CEL

Series

Accession:: GSE19314

ID:: 200019314

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45872.

UCSF sarcoidosis and hypersensitivity pneumonitis cohort: peripheral blood mononuclear cells

Analysis of whole blood from sarcoidosis and hypersensitivity pneumonitis patients. Results provide insight into molecular mechanisms underlying sarcoidosis and hypersensitivity pneumonitis in peripheral blood.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 disease state sets

Platform:: GPL570
Series:: GSE19314
66 Samples

Download data: CEL

DataSet

Accession:: GDS4587

ID:: 4587

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000428343.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. [Third party comment] Samples with identical non-normalized expression values are identified at: https://colab.research.google.com/drive/1swvQGf-ZLAWnZw-7bOCmsypzzAnCDGUR#scrollTo=mIqv_oTHc6ns

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
356 Samples

Download data

Series

Accession:: GSE42834

ID:: 200042834

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428324.

Microarray study using whole blood and purified leucocyte populations from healthy controls and patients with tuberculosis or sarcoidosis with tuberculosis and sarcoidosis

(Submitter supplied) Whole blood and purified leucocyte populations were compared to determine which cell types the whole blood interferon-inducible signature, found in both tuberculosis and sarcoidosis, was present in. This study agreed with previous publication that the neutrophil was the dominant cell in tuberculosis and also showed it was the dominant cell type in sarcoidosis.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
90 Samples

Download data: TXT

Series

Accession:: GSE42832

ID:: 200042832

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428315.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (sarcoidosis)

(Submitter supplied) This study used whole blood transcriptional signatures from patients with sarcoidosis before and during immunosuppressive treatment

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
17 Samples

Download data: TXT

Series

Accession:: GSE42831

ID:: 200042831

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428306.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (training)

(Submitter supplied) This study used whole blood transcriptional signatures from patients with tuberculosis compared to those with similar pulmonary diseases, sarcoidosis, pneumonia and primary lung cancer. TB and sarcoidosis had similar signatures that were distinct from pneumonia and lung cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
95 Samples

Download data: TXT

Series

Accession:: GSE42830

ID:: 200042830

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428277.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (pneumonia treated)

(Submitter supplied) This study used whole blood transcriptional signatures from patients with pneumonia before and after succesful antibiotic treatment

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
10 Samples

Download data: TXT

Series

Accession:: GSE42827

ID:: 200042827

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428268.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (test)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
102 Samples

Download data: TXT

Series

Accession:: GSE42826

ID:: 200042826

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000428259.

Human whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (validation)

(Submitter supplied) This study used whole blood transcriptional signatures from patients with tuberculosis, sarcoidosis and healthy controls.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
42 Samples

Download data: TXT

Series

Accession:: GSE42825

ID:: 200042825

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20015767110.

Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas

(Submitter supplied) Rationale: Despite the availability of multi-“omics” strategies, insights into the etiology and pathogenesis of sarcoidosis have been elusive. This is partly due to the lack of reliable preclinical models and a paucity of validated biomarkers. As granulomas are a key feature of sarcoidosis, we speculate that direct genomic interrogation of sarcoid tissues, may lead to identification of dysregulated gene pathways or biomarker signatures. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
31 Samples

Download data: FASTA, TSV, TXT

Series

Accession:: GSE157671

ID:: 200157671

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20014803611.

Lung transcriptional profiling of pulmonary tuberculosis, adenocarcinoma and sarcoidosis patients using RNA-Seq

(Submitter supplied) Purpose: Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), has long been associated with the development of lung adenocarcinoma (LUAD) and sarcoidosis. These chronic lung diseases share histopathological similarities that challenge differential diagnosis. Methods: Human lung tissues were used for total RNA extraction with RNeasy Plus Mini Kit (Qiagen) according to the manufacturer’s protocol. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
20 Samples

Download data: TXT

Series

Accession:: GSE148036

ID:: 200148036

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20001653812.

Genome-wide gene expression profile analysis in pulmonary sarcoidosis

(Submitter supplied) We hypothesized that tissue genome-wide gene expression analysis, coupled with gene network analyses of differentially expressed genes, would provide novel insights into the pathogenesis of pulmonary sarcoidosis. Keywords: Disease state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3580
Platform:: GPL570
12 Samples

Download data: CEL

Series

Accession:: GSE16538

ID:: 200016538

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 358013.

Pulmonary sarcoidosis

Analysis of lungs from patients with pulmonary sarcoidosis (PS). PS is characterized by the granulomatous inflammation of the lung. Results provide insight into the molecular pathogenesis of PS.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL570
Series:: GSE16538
12 Samples

Download data: CEL

DataSet

Accession:: GDS3580

ID:: 3580

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20001997614.

Gene expression analysis of lung biopsies from patients with two different forms of pulmonary sarcoidosis

(Submitter supplied) Approximately 60-70% of patients with pulmonary sarcoidosis have a good outcome, with disease that resolves spontaneously. It is unclear why some patients progress to fibrotic disease, and there is currently no marker that differentiates these patients from those with self-limiting lung disease. Using the Affymetrix Human Gene 1.0 ST Array, we examined gene expression in lung tissue samples obtained using bronchoscopic transbronchial biopsy from 8 patients with active but self-limiting pulmonary sarcoidosis and 7 with active, progressive, fibrotic pulmonary disease. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3705
Platform:: GPL6244
15 Samples

Download data: CEL

Series

Accession:: GSE19976

ID:: 200019976

Select item 370515.

Progressive pulmonary sarcoidosis

Comparison of lungs from patients with nodular self-limiting pulmonary sarcoidosis (PS) to those with progressive fibrotic PS. About 60-70% of patients with PS have disease that resolves spontaneously, the rest follow a chronic course. Results provide insight into the pathogenesis of progressive PS.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL6244
Series:: GSE19976
15 Samples

Download data: CEL

DataSet

Accession:: GDS3705

ID:: 3705

Select item 20008345616.

The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis

(Submitter supplied) Background: Mycobacterium tuberculosis infection is a leading cause of infectious death worldwide. Gene-expression microarray studies profiling the blood transcriptional response of tuberculosis (TB) patients have been undertaken in order to better understand the host immune response as well as to identify potential biomarkers of disease. To date most of these studies have focused on pulmonary TB patients with gene-expression profiles of extra-pulmonary TB patients yet to be compared to those of patients with pulmonary TB or sarcoidosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
202 Samples

Download data: TXT

Series

Accession:: GSE83456

ID:: 200083456

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20017456617.

Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets II

(Submitter supplied) We hypothesised that whole transcriptome analysis of human TB granulomas isolated by laser capture microdissection could identify therapeutic targets, and that comparison with a non-infectious granulomatous disease, sarcoidosis, would identify disease-specific pathological mechanisms. Bioinformatic analysis of RNAseq data identified numerous shared pathways between TB and sarcoidosis lymph nodes, and also specific clusters demonstrating TB results from a dysregulated inflammatory immune response. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
36 Samples

Download data: TXT

Series

Accession:: GSE174566

ID:: 200174566

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20017444318.

Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17303
24 Samples

Download data: TXT

Series

Accession:: GSE174443

ID:: 200174443

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20005615319.

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

(Submitter supplied) Whole-genome expression profiling on a cohort of TB patients. Tuberculosis patients above 15 years of age were recruited from an outpatient tuberculosis clinic in central Jakarta (Indonesia). Randomly selected control subjects with the same sex and age (+/-10%) were recruited from neighboring households, with first degree relatives excluded.