GEO DataSets

(Submitter supplied) Analysis of photodynamic therapy with hypericin of nasopharyngeal carcinoma cells CNE-2 in different time-points at gene expression level. The hypothesis tested in the present study was that HY-PDT could induce apoptosis on CNE-2 cells via intrinsic pathways. Results provide important information of the response of apoptosis, such as specific oxidative stress genes, mitochondrial related genes, cell cycle related genes, etc.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL7363

6 Samples

Download data: TXT

(Submitter supplied) Copper-based chemotherapeutic compounds Casiopeinas, have been presented as able to promote selective programmed cell death in cancer cells, thus being proper candidates for targeted cancer therapy. DNA fragmentation and apoptosis -in a process mediated by reactive oxygen species- for a number of tumor cells, have been argued to be the main mechanisms. However, a detailed functional mechanism (a model) is still to be defined and interrogated for a wide variety of cellular conditions; before establishing settings and parameters needed for their wide clinical application. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4665

Platform:

GPL570

6 Samples

Download data: CEL

Analysis of cervical cancer HeLa cells treated with casiopeinas II-gly (40µM) for 6 hours. Casiopeínas are copper-containing compounds that can promote selective programmed cell death in cancer cells. Results provide insight into the molecular mechanisms underlying casiopeína-induced apoptosis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL570

Series:

GSE41827

6 Samples

Download data: CEL