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Links from GEO DataSets

Items: 4

1.

Transcriptional Alterations of Hamstring Muscle Contractures in Children with Cerebral Palsy

(Submitter supplied) Cerebral palsy is primarily an upper motor neuron disease that results in a spectrum of progressive movement disorders. Secondary to the neurological lesion, muscles from patients with cerebral palsy are often spastic and form debilitating contractures that limit range of motion and joint function. With no genetic component, the pathology of skeletal muscle in cerebral palsy is a response to aberrant neurological input in ways that are not fully understood. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4353
Platform:
GPL571
40 Samples
Download data: CEL, TXT
Series
Accession:
GSE31243
ID:
200031243
2.
Full record GDS4353

Cerebral Palsy: skeletal muscle biopsies

Analysis of gracilis and semitendinosus muscle biopsies from pediatric cerebral palsy (CP) patients. Muscles from CP patients are spastic and form contractures limiting range of motion and joint function. Results provide insight into molecular basis of skeletal muscle response to CP.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 2 tissue sets
Platform:
GPL571
Series:
GSE31243
40 Samples
Download data: CEL
3.

Unique Transcriptional Profile in Wrist Muscles From Cerebral Palsy Patients

(Submitter supplied) Cerebral palsy is caused be an upper motor neuron lesion which casues spasticity as well as secondary effects on muscle . Muscle from cerebral palsy patients is has been shown to be smaller, with more ECM and longer sarcomere lengths We used microarrays to globally investigate the transcriptional adaptations of cerebral palsy muscle and research which muscle pathways are altered in the diseased state Keywords: Disease state analysis
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3644
Platform:
GPL96
16 Samples
Download data: CEL, CHP, TXT
Series
Accession:
GSE11686
ID:
200011686
4.
Full record GDS3644

Cerebral palsy: wrist muscles

Analysis of wrist muscle extensors and flexors of cerebral palsy (CP) patients. CP is an upper motor neuron disease that results in a progressive movement disorder. Muscles of CP patients often become spastic. Results provide insight into the molecular alterations in spastic muscles of CP patients.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 8 individual, 2 tissue sets
Platform:
GPL96
Series:
GSE11686
16 Samples
Download data: CEL, CHP
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