GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus; Rattus norvegicus

Type:

Expression profiling by array

9 related Platforms

115 Samples

Download data: CEL

(Submitter supplied) This program addresses the gene signature associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in adipose tissue of the db/db mice compared to the control db/+ mice?

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL13717

6 Samples

Download data: TXT

(Submitter supplied) To understand the effects of knocking out the 5-LO gene on gene expression in key metabolic target tissues liver.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3562

19 Samples

Download data: TXT

(Submitter supplied) This program addresses the gene signature associated with LPS-treated liver in rat. Specifically, which genes are differentially expressed in livers of the Sprague Dawley rats treated with LPS?

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL15569

8 Samples

Download data: TXT

(Submitter supplied) This program aims at identifying a muscle gene signature associated with aging in rat sarcopenia model

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL15572

10 Samples

Download data: CEL, TXT

(Submitter supplied) This program aims at identifying the lung gene signature associated with inflammation and emphysema in IL-1b-Tg mouse COPD model to facilitate understanding of the disease mechanism and therapeutic compound testing

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6794

8 Samples

Download data: CEL, TXT

(Submitter supplied) This program aims at identifying a skin gene signature associated with inflammation pain in rat CGN model

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL15572

9 Samples

Download data: CEL, TXT

(Submitter supplied) This program addresses the gene signature associated with DRG in the Chung rat model for neuropathic pain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL2050

8 Samples

Download data: TXT

(Submitter supplied) This program addresses the gene signature associated with brain (cortex) in the tMCAO rat model for stroke.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL3631

8 Samples

Download data: TXT

(Submitter supplied) This program addresses the molecular basis of beta-cell failure associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in pancreatic islets of the db/db mice compared to the control db/+ mice?

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL8591

10 Samples

Download data: TXT

(Submitter supplied) This program addresses the molecular basis of beta-cell failure associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in pancreatic islets of the db/db mice compared to the control db/+ mice?

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3677

6 Samples

Download data: TXT

(Submitter supplied) Transgenic (Tg) mice over-expressing TGFb1 in a lung-specific manner display airway inflammation and fibrosis, phenotypes relevant to human COPD and asthma. This model system provides a platform for identifying and validating genes/pathways involved in these disease pathogeneses.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3677

8 Samples

Download data: TXT

(Submitter supplied) This program aims at identifying the lung gene signature associated with OVA-challenged mouse asthma model to facilitate understanding of the disease mechanism and therapeutic compound testing

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3677

9 Samples

Download data: TXT

(Submitter supplied) This program aimed to understand gene expression changes in aorta during atherosclerotic lesion progression with an objective to identify genes that may present new opportunities for drug intervention

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3677

6 Samples

Download data: TXT

(Submitter supplied) To validate the predicted Sh2b3 derived gene regulatory subnetwork using integrative network approach in human population study, we examined the gene expression levels of whole blood in WT (wild-type) and Sh2b3-/- mice by RNA sequencing, and identified the differentially expressed genes.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

8 Samples

Download data: FPKM_TRACKING

(Submitter supplied) To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6J x A/J F2 (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the population. We have identified a large number of trait QTLs including loci driving variation in cardiac function on chromosomes 2 and 6 and a hotspot for adiposity, energy metabolism, and glucose traits on chromosome 8. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3677

1456 Samples

Download data: TXT

(Submitter supplied) We sequenced mammary gland samples of MMTV-PyMT mouse from 4 stages (hyperplasia at week 6, adenoma/MIN at week 8, early carcinoma at week 10, and late carcinoma with lung metastasis at week 12) during tumor progression.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL17021

24 Samples

Download data: CSV

(Submitter supplied) Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease with complex etiopathogenesis. Here we use Affymetrix U133 plus 2.0 microarray gene expression data from human parotid tissue. Parotid gland tissues were harvested from 17 pSS and 14 14 non-pSS sicca patients and 18 controls. The data were used in the following article: Nazmul-Hossain ANM, Pollard RPE, Kroese FGM, Vissink A, Kallenberg CGM, Spijkervet FKL, Bootsma H, Michie SA, Gorr SU, Peck AB, Cai C, Zhou H, Horvath S, Wong DTW (2012) Systems Analysis of Primary Sjögren’s Syndrome Pathogenesis in Salivary Glands: Comparative Pathways and Molecular Events in Humans and a Mouse Model.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

49 Samples

Download data: CEL

(Submitter supplied) Wiskott-Aldrich syndrome (WAS) predisposes patients to leukemia and lymphoma. WAS is caused by mutations in the protein WASP which impair its interaction with the WIPF1 protein. Here, we aim to identify a module of WIPF1-coexpressed genes and to assess its use as a prognostic signature for colorectal cancer, glioma, and breast cancer patients. Two public colorectal cancer microarray data sets were used for discovery and validation of the WIPF1 co-expression module. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

62 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background Comparison of whole genome expression data of amygdala and hippocampus of both C57BL/6J and A/J mouse inbred strains using a network approach

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6103

35 Samples

Download data: TXT