Similar studies for GEO DataSets (Select 200035813) - GEO DataSets

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Items: 12

Select item 2000358131.

miRNA profile of exosomes released from PC-3 cells compared to parent cells

(Submitter supplied) Exosomes are small extracellular vesicles released through fusion of multivesicular bodies with the plasma membrane. The aim of this study was to investigate whether there are any differences in miRNAs in exosomes secreted from the prostate cancer cell line PC-3 and in parent cells, as well as to investigate whether there are any differences in miRNAs in cell lysates from PC-3 cells and the non-cancerous prostate cell line RWPE-1.

Organism:: Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8

Type:: Non-coding RNA profiling by array

Platform:: GPL11434
9 Samples

Download data: TXT

Series

Accession:: GSE35813

ID:: 200035813

Select item 2000836692.

Plasma Exosome microRNAs are Indicative of Breast Cancer

(Submitter supplied) Introduction: microRNAs are promising candidate breast cancer biomarkers due to their cancer-specific expression profiles. However, efforts to develop circulating breast cancer biomarkers are challenged by the heterogeneity of microRNAs in the blood. To overcome this challenge, we aimed to develop a molecular profile of microRNAs specifically secreted from breast cancer cells. Our first step towards this direction relates to capturing and analyzing the contents of exosomes, which are small secretory vesicles that selectively encapsulate microRNAs indicative of their cell of origin. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL15520
6 Samples

Download data: XLSX

Series

Accession:: GSE83669

ID:: 200083669

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000582833.

Gene expression profiling of mouse bone marrow-derived macrophages (RNA-Seq)

(Submitter supplied) Bone marrow (BM) cells were obtained by flushing the long bones of 8-week old C57BL/6 mice. BM cells were then were plated in macrophage SFM medium (Life Technologies) supplemented with penicillin-streptomycin and CSF-1 (Peprotech, 100 ng/ml) and cultured for one week to allow macrophage differentiation. BMDMs were polarized by adding IL-4 to the medium (40 ng/ml, Peprotech) for 72h or left untreated.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL17021
8 Samples

Download data: GTF, TXT

Series

Accession:: GSE58283

ID:: 200058283

PubMed Similar studies SRA Run Selector

Select item 2000971234.

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

(Submitter supplied) Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles derived from cellular multivesicular bodies that are enriched in specific miRNAs, potentially providing a disease-specific diagnostic signature. To assess the value of exosome miRNAs as biomarkers for T1DM, miRNA expression in plasma-derived exosomes was measured. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL17537
24 Samples

Download data: RCC, TXT

Series

Accession:: GSE97123

ID:: 200097123

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000619785.

Expression profiles of microRNA in bovine raw milk exosome and supernatant without exosome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Bos taurus

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL19259 GPL11649
4 Samples

Download data: TXT

Series

Accession:: GSE61978

ID:: 200061978

Select item 2000619776.

Expression profiles of microRNA in bovine raw milk exosome and supernatant without exosome [mRNA array]

(Submitter supplied) We have reported that microRNAs are present in human, bovine, and rat milk whey. Milk whey miRNAs were resistant to acidic condition and to RNase. Thus, milk miRNAs were thought to be present packaged into membrane vesicles like exosome. However, body fluid miRNAs have been reported that there are in different forms. To clarify which miRNAs species are exist in exosome and which species are exist in another form, we used bovine raw milk and purified total RNA from exosome fraction and ultracentrifugated supernatant fraction, and analyzed by miRNA microarray.

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL11649
2 Samples

Download data: TXT

Series

Accession:: GSE61977

ID:: 200061977

Select item 2000619767.

Expression profiles of microRNA in bovine raw milk exosome and supernatant without exosome [miRNA array]

Organism:: Bos taurus

Type:: Non-coding RNA profiling by array

Platform:: GPL19259
2 Samples

Download data: TXT

Series

Accession:: GSE61976

ID:: 200061976

Select item 2001093568.

Cellular and extracellular vesicle miRNA profiles in GFP-PC3 and cavin-1-PC3 cell lines.

(Submitter supplied) This study assessed exosomal and cellular miRNA profiles in GFP-PC3 cells and ectopically expressed cavin-1 PC3 cell lines. To understand the consequences of cavin-1 on extracellular vesicle (EV)-contained miRNAs, a small RNA-seq experiment was performed on cells and secreted EVs for GFP-PC3 and cavin-1-PC3 cells. Small RNA were selected for sequencing using the NEBNext Small RNA library Prep Kit. Libraries were size selected using a Perkin Elmer Labchip XT. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL18573
12 Samples

Download data: TXT

Series

Accession:: GSE109356

ID:: 200109356

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000887559.

Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL17061 GPL13915
19 Samples

Download data: TXT

Series

Accession:: GSE88755

ID:: 200088755

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008875410.

Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing [miRNA]

(Submitter supplied) Cells secrete extracellular RNA (exRNA) to their surrounding environment and exRNA has been found in many body fluids such as blood, breast milk and cerebrospinal fluid. However, there are conflicting results regarding the nature of exRNA. Here, we have separated two distinct exRNA profiles released by mast cells, here termed high-density (HD) and low-density (LD) exRNA. The exRNA in both fractions was characterized by microarray and next-generation sequencing. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL17061
9 Samples

Download data: TXT

Series

Accession:: GSE88754

ID:: 200088754

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008875311.

Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing [total RNA]

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13915
10 Samples

Download data: TXT

Series

Accession:: GSE88753

ID:: 200088753

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002532012.

Characterisation of mRNA and microRNA in human mast cell exosomes and their transfer to other mast cells and blood CD34 progenitor cells

(Submitter supplied) Background: Exosomes are nanovesicles of endocytic origin believed to be involved in communication between cells. Recently, it has been shown that mast cell exosomes contain RNA named "exosomal shuttle RNA". The aim of this study was to evaluate whether exosomal shuttle RNA could play a role in the communication between human mast cells and between human mast cells and human CD34 positive progenitor cells. more...

Organism:: Mus musculus; Human gammaherpesvirus 8; Homo sapiens; Human betaherpesvirus 5; Human immunodeficiency virus 1; Rattus norvegicus; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; human gammaherpesvirus 4; Betapolyomavirus macacae