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Links from GEO DataSets

Items: 20

1.

RNA profiling from ovarian and prostate FFPE specimens

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
54 Samples
Download data: CEL
Series
Accession:
GSE54809
ID:
200054809
2.

RNA profiling from ovarian FFPE specimens (Nanostring)

(Submitter supplied) To study feasibility of gene expression profiling from FFPE tissues using NanoString nCounter platform, we designed a pilot study utilizing samples from ovarian cancer cohort. We selected samples from large-scale epidemiologic studies and clinical trials representative of a wide variety of fixation times, block ages and block storage conditions.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL18292
24 Samples
Download data: TXT
Series
Accession:
GSE55056
ID:
200055056
3.

RNA profiling from prostate FFPE specimens (Nanostring)

(Submitter supplied) To study feasibility of gene expression profiling from FFPE tissues using NanoString nCounter platform, we designed a pilot study utilizing samples from prostate cancer cohort. We selected samples from large-scale epidemiologic studies and clinical trials representative of a wide variety of fixation times, block ages and block storage conditions.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL18292
24 Samples
Download data: TXT
Series
Accession:
GSE55055
ID:
200055055
4.

RNA profiling from prostate FFPE specimens

(Submitter supplied) To study feasibility of gene expression profiling from FFPE tissues using NuGen amplified mRNA hybridized on Affymetrix GeneChip Human Gene 1.0 ST arrays, we designed a pilot study utilizing samples from prostate cancer cohort. We selected samples from large-scale epidemiologic studies and clinical trials representative of a wide variety of fixation times, block ages and block storage conditions.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
30 Samples
Download data: CEL
Series
Accession:
GSE54808
ID:
200054808
5.

RNA profiling from ovarian FFPE specimens

(Submitter supplied) To study feasibility of gene expression profiling from FFPE tissues using NuGen amplified mRNA hybridized on Affymetrix GeneChip Human Gene 1.0 ST arrays, we designed a pilot study utilizing samples from prostate cancer cohort. We selected samples from large-scale epidemiologic studies and clinical trials representative of a wide variety of fixation times, block ages and block storage conditions.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
24 Samples
Download data: CEL
Series
Accession:
GSE54807
ID:
200054807
6.

Global gene expression analysis of fresh-frozen, furan-exposed mouse liver using RNA-seq [polyA enrichment]

(Submitter supplied) Furan is a mouse and rat hepatocarcinogen. We sought to determine if furan-induced gene expression changes could be detected in paired fresh-frozen and formalin-fixed paraffin embedded (FFPE) samples using RNA-seq (polyA-enrichment protocol). All samples in this study (fresh-frozen, 18 hours in formalin, 3 weeks in formalin) were also examined using one- and two-colour microarrays and RNA-seq (ribo-depletion protocol) in order to determine the effect of the technology on gene expression profiles.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
24 Samples
Download data: TXT
Series
Accession:
GSE64371
ID:
200064371
7.

Global gene expression analysis of fresh-frozen, furan-exposed mouse liver using RNA-seq [ribo-depletion]

(Submitter supplied) Furan is a mouse and rat hepatocarcinogen. We sought to determine if furan-induced gene expression changes could be detected in paired fresh-frozen and formalin-fixed paraffin embedded (FFPE) samples using RNA-seq (ribo-depletion protocol). All samples in this study (fresh-frozen, 18 hours in formalin, 3 weeks in formalin) were also examined using one- and two-colour microarrays and RNA-seq (polyA-enrichment protocol) in order to determine the effect of the technology on gene expression profiles.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
24 Samples
Download data: TXT
Series
Accession:
GSE64370
ID:
200064370
8.

Global gene expression analysis in paired fresh-frozen and FFPE furan-exposed mouse liver samples

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL10787
122 Samples
Download data: TXT, XLSX
Series
Accession:
GSE62843
ID:
200062843
9.

Global gene expression analysis of fresh-frozen, furan-exposed mouse liver using one-colour Agilent microarrays

(Submitter supplied) Furan is a mouse and rat hepatocarcinogen. We sought to determine if furan-induced gene expression changes could be detected in paired fresh-frozen and formalin-fixed paraffin embedded (FFPE) samples using one-colour microarrays. All samples in this study (fresh-frozen, 18 hours in formalin, 3 weeks in formalin) were also examined using two-colour microarrays and RNA-seq (ribo-depletion and polyA-enrichment protocols) in order to determine the effect of the technology on gene expression profiles.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
8 Samples
Download data: TXT
Series
Accession:
GSE62842
ID:
200062842
10.

Global gene expression analysis of formalin-fixed paraffin-embedded (FFPE), furan-exposed mouse liver using one-colour Agilent microarrays

(Submitter supplied) Furan is a mouse and rat hepatocarcinogen. We sought to determine if furan-induced gene expression changes could be detected in paired fresh-frozen and formalin-fixed paraffin embedded (FFPE) samples using one-colour microarrays. To determine the effect of time-in-formalin on gene expression signatures we performed microarray analysis of livers that were fixed in formalin for 18 hours or 3 weeks. All samples (fresh-frozen, 18 hours in formalin, 3 weeks in formalin) were also examined using two-colour microarrays and RNA-seq (ribo-depletion and polyA-enrichment protocols) in order to determine the effect of the technology on gene expression profiles.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
50 Samples
Download data: TXT
Series
Accession:
GSE62840
ID:
200062840
11.

Global gene expression analysis of formalin-fixed paraffin-embedded (FFPE), furan-exposed mouse liver using two-colour Agilent microarrays

(Submitter supplied) Furan is a mouse and rat hepatocarcinogen. We sought to determine if furan-induced gene expression changes could be detected in paired fresh-frozen (GSE48644) and formalin-fixed paraffin embedded (FFPE; this study) samples using two-colour microarrays. To determine the effect of time-in-formalin on gene expression signatures we performed microarray analysis of livers that were fixed in formalin for 18 hours or 3 weeks. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
16 Samples
Download data: TXT
Series
Accession:
GSE62838
ID:
200062838
12.

Preparation of archival formalin-fixed paraffin-embedded mouse liver samples for use with the Agilent gene expression microarray platform

(Submitter supplied) For decades, formalin-fixing and paraffin embedding (FFPE) has been routinely used to preserve tissue samples for histological analysis. Global gene expression analysis of these archival tissues has the potential to greatly advance research attempting to link perturbations in molecular pathways to disease outcome. We investigated 16-year-old FFPE mouse liver samples treated with phenobarbital and created a protocol for their analysis using Agilent gene expression arrays. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL13912
28 Samples
Download data: TXT
Series
Accession:
GSE40990
ID:
200040990
13.

Clinical relevance of DNA microarray analyses using archival formalin-fixed paraffin-embedded breast cancer specimens

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL8432 GPL6883
50 Samples
Download data
Series
Accession:
GSE23386
ID:
200023386
14.

Gene profiling using archival formalin-fixed paraffin-embedded breast cancer specimens can generate informative microarray data: A comparison with matched fresh fine needle aspiration biopsy samples (FNA samples)

(Submitter supplied) The Formalin-Fixed Paraffin-Embedded (FFPE) samples on selected breast cancer subtypes (ER+/Her2-, ER+/Her2+, ER-/Her2+, and ER-/Her2-) and their paired fresh fine needle aspirated biopsies (FNA) were investigated. The cases represented different subtypes of breast cancers based on their clinical receptors ER (E) and Her2 (H) status to demonstrate the ability of gene profiles to differentiate these tumors. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
25 Samples
Download data: TXT
Series
Accession:
GSE23385
ID:
200023385
15.

Gene profiling using archival formalin-fixed paraffin-embedded breast cancer specimens can generate informative microarray data: A comparison with matched fresh fine needle aspiration biopsy samples (FFPE samples)

(Submitter supplied) The Formalin-Fixed Paraffin-Embedded (FFPE) samples on selected breast cancer subtypes (ER+/Her2-, ER+/Her2+, ER-/Her2+, and ER-/Her2-) and their paired fresh fine needle aspirated biopsies (FNA) were investigated. The cases represented different subtypes of breast cancers based on their clinical receptors ER (E) and Her2 (H) status to demonstrate the ability of gene profiles to differentiate these tumors. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL8432
25 Samples
Download data: TXT
Series
Accession:
GSE23384
ID:
200023384
16.

Gene-expression profiles of archived section of formalin-fixed paraffin-embedded (AS-FFPE) liver and tumor tissues from hepatocellular carcinoma patients (Illumina and Nanostring)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL17230 GPL13369
160 Samples
Download data
Series
Accession:
GSE47595
ID:
200047595
17.

Gene-expression profiles of archived section of formalin-fixed paraffin-embedded (AS-FFPE) liver tissues from hepatocellular carcinoma patients

(Submitter supplied) Background and Aims Formalin-fixed, paraffin-embedded (FFPE) tissue is the most commonly available form of archived clinical specimens, which are often stored as thin sections on glass slides. RNA isolated from such archived section (AS) of FFPE tissue is more degraded compared to freshly cut (FC) FFPE section because of prolonged air exposure. In this study, we evaluated performance of transcriptome profiling-based disease classification in AS-FFPE tissue. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17230
24 Samples
Download data: TXT
Series
Accession:
GSE47594
ID:
200047594
18.

Gene-expression profiles of archived section of formalin-fixed paraffin-embedded (AS-FFPE) liver and tumor tissues from hepatocellular carcinoma patients

(Submitter supplied) Background and Aims Formalin-fixed, paraffin-embedded (FFPE) tissue is the most commonly available form of archived clinical specimens, which are often stored as thin sections on glass slides. RNA isolated from such archived section (AS) of FFPE tissue is more degraded compared to freshly cut (FC) FFPE section because of prolonged air exposure. In this study, we evaluated performance of transcriptome profiling-based disease classification in AS-FFPE tissue. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13369
136 Samples
Download data: TXT
Series
Accession:
GSE46444
ID:
200046444
19.

Whole-Genome Gene Expression Profiling of Formalin-Fixed, Paraffin-Embedded Ovarian Tumor Tissue Samples: Dilutions

(Submitter supplied) Performance assayed with formalin-fixed, paraffin-embedded (FFPE) ovarian tumor tissues.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
24 Samples
Download data: TXT
Series
Accession:
GSE18769
ID:
200018769
20.

Whole-Genome Gene Expression Profiling of Formalin-Fixed, Paraffin-Embedded Ovarian Tumor Tissue Samples: Ratios

(Submitter supplied) Performance assayed with formalin-fixed, paraffin-embedded (FFPE) ovarian tumor tissues.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
42 Samples
Download data: TXT
Series
Accession:
GSE18767
ID:
200018767
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