Similar studies for GEO DataSets (Select 200055849) - GEO DataSets

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Items: 2

Select item 2000558491.

Simultaneous Host-Pathogen transcriptome analysis during Granulibacter bethesdensis infection of normal and chronic granulomatous disease neutrophils

(Submitter supplied) Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis is an emerging Gram-negative pathogen in CGD that resists killing by CGD PMN and inhibits PMN apoptosis through unknown mechanisms. more...

Organism:: Homo sapiens; Chlamydia muridarum; Staphylococcus epidermidis RP62A; Staphylococcus aureus subsp. aureus MW2; Chlamydia pneumoniae AR39; Granulibacter bethesdensis; Borreliella burgdorferi B31; Coxiella burnetii RSA 493; Chlamydia trachomatis D/UW-3/CX; Staphylococcus haemolyticus JCSC1435; Coxiella burnetii; Rickettsia rickettsii; Staphylococcus epidermidis ATCC 12228; Chlamydia caviae GPIC

Type:: Expression profiling by array

Platforms:: GPL570 GPL4692
123 Samples

Download data: CEL, CHP

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Accession:: GSE55849

ID:: 200055849

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000009352.

NIH/NIAID Chronic Granulomatous Disease Neutrophils

(Submitter supplied) Polymorphonuclear leukocytes (PMNs) were obtained from healthy individuals (Healthy1, Healthy2, Healthy3, and Healthy4) or patients with X-linked chronic granulomatous disease (XCGD1, XCGD2, XCGD3, XCGD4, XCGD5, and XCGD6). The studies were performed in accordance with a protocol approved by the Institutional Review Board for Human Subjects, National Institute of Allergy and Infectious Diseases, and the Institutional Review Board for Human Subjects at the University of Iowa. more...