GEO DataSets

(Submitter supplied) Microarrays were used to analyze the gene expression in endoscopic-derived intestinal mucosal biopsies from patients with inflammatory bowel disease (IBD) and controls

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

116 Samples

Download data: CEL

(Submitter supplied) Analysis of the effects of different vaccine viral vectors on gene expression in human monocyte-derived dendritic cells (MDDCs), which were generated from isolated monocytes from 3 different donors. The goal in this study was to find the difference of gene expression in human MDDCs upon ALVAC and Ad5 vrial vectors infection.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

6 Samples

Download data: IDAT, TXT

(Submitter supplied) The development of oral squamous cell carcinoma (OSCC) is a multistep process requiring the accumulation of genetic alterations. To identify genes responsible for OSCC development, we performed high-density single-nucleotide polymorphism array analysis and genome-wide gene expression profiling on OSCC tumors. These analyses identified "absent in melanoma (AIM2)" and "interferon-inducible gene 16 (IFI16)," mapped to the hematopoietic IFN-inducible nuclear proteins with 200-amino acid repeat (HIN-200) gene cluster in the amplified region of chromosome 1q23, with overexpression in OSCCs. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by SNP array; SNP genotyping by SNP array

Platform:

GPL3720

33 Samples

Download data: CEL, CHP

(Submitter supplied) The body’s first line of defense against environmental assaults, the skin’s barrier, is maintained by epidermal stem cells (EpdSCs). Despite EpdSC’s vulnerability to inflammatory pressures, neither their primary response nor its enduring consequences are understood. Here, we unearth a prolonged memory to acute inflammation that enables EpdSCs to hasten barrier restoration following subsequent tissue damage. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL21103 GPL17021

28 Samples

Download data: BW, TAB

(Submitter supplied) About 40% IBD patients treated with anti-TNF antibodies do not respond to therapy. Baseline biomarkers of response are therefore of interest. By combining computational deconvolution of gene expression and meta-analysis approaches we identified cellular biomarkers in tissue (validated in 2 cohorts by IHC of biopsies), and investigated associated gene biomarkers in blood. This dataset provides data from the validation cohort III (blood).

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23159

22 Samples

Download data: CEL