GEO DataSets

(Submitter supplied) We identified Gyc76C as a novel regulator in Drosophila innate immunity We used microarray to examine gene expression in Gyc76C mutant lines.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

10 Samples

Download data: CEL, CHP

(Submitter supplied) We identified Gyc76C as a novel regulator in Drosophila innate immunity We used microarray to examine gene expression in Gyc76C mutant adult.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

6 Samples

Download data: CEL, CHP

(Submitter supplied) We identified Gyc76C as a novel regulator in Drosophila innate immunity We used microarray to examine gene expression in Gyc76C overexpressed lines.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

4 Samples

Download data: CEL, CHP

(Submitter supplied) This micro-array helps establishing the function of Akirin, a nuclear protein with unknown domains, a putative interacting partner, in the transcriptional regulation of the targets of Relish, a NF-kB factor required to fight Gram(-) bacteria infection in Drosophila melanogaster.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL17080

18 Samples

Download data: TXT

(Submitter supplied) Purpose: To compared the gene expression profiles of splenocytes from wild type and UBLA4/GdX (Ubiquitin-like protein 4A, also named GdX) knockout mice upon LPS stimulation. Methods: GdX+/Y and GdX-/Y mice were injected with LPS. Their splenocytes were collected at different time (90min or 6 hrs), and then performed RNA-sequencing analysis. We sequence the samples used BGISEQ-500 platform. Results: The average mapping ratio with reference genome is 93.42%, the average mapping ratio with gene is 83.40%; A total of 17,920 genes were detected.A number of NF-κB targeting genes, such as IL-6, IL-1a and IL-12, have dramatic higher expressions in the splenocytes of GdX+/Y mice than that of GdX-/Y mice. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23479

7 Samples

Download data: XLS

(Submitter supplied) The maintenance of innate immune homeostasis is critical for animal survival to combat pathogens. Although many positive or negative protein factors have been identified, little is known about the long non-coding RNA that regulates the Toll pathway. Herein, we have discovered a novel lncRNA-CR11538 highly activated during the Drosophila response to gram+ bacterial infection. The transient overexpression of CR11538 inhibited the expression of antimicrobial peptides (Drosomycin and Metchnikowin) in vivo to suppress Toll signaling pathway. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13304

6 Samples

Download data: XLSX