Similar studies for GEO DataSets (Select 200112964) - GEO DataSets

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Items: 10

Select item 2001129641.

Differential expression data of BMDMs of mice infected with avian influenza influenza A (H7N9) viruses

(Submitter supplied) To clarify the underlying mechanism that regulates the response of iron metabolism to influenza A virus infection, we analyzed gene expression profiles in mouse, bone marrow-derived macrophages (BMDMs) infected with H7N9 virus. In addition, We also analysed the chemokine, inflammation, innate-immunity, lipid-metabolism, transcription mRNA level by micrroarray. So, we gain the global transcriptional response in the BMDMs of mice infected with H7N9 virus.

Organism:: Mus musculus; Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL24871
8 Samples

Download data: GPR

Series

Accession:: GSE112964

ID:: 200112964

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002265932.

CK1α suppresses autoimmunity by restraining the cGAS-STING signaling

(Submitter supplied) Stimulator of interferon genes (STING), the central hub protein of the cGAS-STING signaling, is essential for type I IFN production of innate immunity. However, prolonged or excessive activation of STING is highly related to autoimmune diseases, most of which exhibit the hallmark of elevated expression of type I interferons and IFN-stimulated genes (ISGs). Thus, the activity of STING must be stringently controlled to maintain immune homeostasis. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
12 Samples

Download data: TXT

Series

Accession:: GSE226593

ID:: 200226593

PubMed Similar studies

Select item 2002015083.

Cannabidiol modulates type I IFN response genes and HIV infection in macrophages

(Submitter supplied) To understand the differential expression of CBD on monocytic cells and the mechanisms by which CBD interacts with our immune system and immune cell signaling.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
12 Samples

Download data: TXT

Series

Accession:: GSE201508

ID:: 200201508

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001906974.

Selective autophagic degradation of ATP citrate lyase maintains citrate homeostasis and promotes oocyte maturation

(Submitter supplied) Autophagy is a cellular and energy homeostatic mechanism that contributes to maintain the number of primordial follicles, germ cell survival, and anti-ovarian aging. However, it remains unknown whether autophagy in granulosa cells affects the oocyte maturation. Here, we show a clear tendency of reduced autophagy level in human granulosa cell from women of advanced maternal age, implying a potential negative correlation between autophagy level and oocyte quality. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21273
6 Samples

Download data: TXT

Series

Accession:: GSE190697

ID:: 200190697

PubMed Full text in PMC Similar studies

Select item 2001853175.

mRNA sequencing data of inguinal adipose tissue (iAT) of mice at postnatal day 6 (P6) and 56 (P56)

(Submitter supplied) Non-treated, C57Black/6 male mice were used.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23479
2 Samples

Download data: TXT

Series

Accession:: GSE185317

ID:: 200185317

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001549256.

Transcriptional changes caused by ablation of neuropeptide FF receptor-1 (NPFFR1)

(Submitter supplied) We compared inguinal fat depots of wild-type (WT) and NPFFR1 deficient (NPFFR1-KO) mice at postnatal day 6. In this project, we sequence 6 samples used DNBseq platform, averagely generating about 32.03 M reads per sample. The average mapping ratio with reference genome is 95.49%, the average mapping ratio with gene is 73.18%; A total of 19,886 genes were detected.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28457
6 Samples

Download data: XLS

Series

Accession:: GSE154925

ID:: 200154925

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2002212187.

MAVI1, an Endoplasmic Reticulum-localized Microprotein, Suppresses Antiviral Innate Immune Response by Targeting MAVS on Mitochondrion

(Submitter supplied) Pattern recognition receptors (PRRs)-mediated innate immune responses are critical for host defense against microbial pathogens including RNA/DNA viruses. A growing number of coding genes and genes originally defined as non-coding RNAs (ncRNAs) are found to encode short peptides or proteins, named microproteins. However, the landscape of microproteins in responsive to virus infection and the functions of these microproteins remain uncharacterized. more...