Similar studies for GEO DataSets (Select 200127541) - GEO DataSets

Select item 2001275411.

Gene Expression by granuloma macrophages from resistant and susceptible mice after 4h of phagocytosis of metacyclical Leishmania major

(Submitter supplied) The goal of this experiment was to identify genes which are differentially regulated between Leishmania major- infected granuloma macrophages from mice resistant (C57 Bl/6) and susceptible (BALB/c) to experimental leishmaniasis

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL81
12 Samples

Download data: CEL

Series

Accession:: GSE127541

ID:: 200127541

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Select item 2000104422.

Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE

(Submitter supplied) Leishmania (L) are intracellular protozoan parasites which are able to survive and replicate within the harsh and potentially hostile phago-lysosomal environment of mammalian mononuclear phagocytes. A complex interplay then takes place between the macrophage (MΦ) striving to eliminate the pathogen and the parasite struggling for its own survival. To investigate, at the transcriptional level, this host-parasite conflict in the context of monocyte-derived human MΦs (MDM) infection by L. more...

Organism:: Homo sapiens; Leishmania major

Type:: Expression profiling by SAGE

Platforms:: GPL6471 GPL4
3 Samples

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Series

Accession:: GSE10442

ID:: 200010442

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Select item 2000319973.

Gene Expression data from mouse bone marrow derived macrophages infected by the promastigote form of Leishmania major parasite (P) or Killed parasite (Kp) during a time course of infection

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
96 Samples

Download data: CEL

Series

Accession:: GSE31997

ID:: 200031997

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Select item 2000319954.

Gene Expression data from Mouse Balb/c Bone marrow derived macrophages infected by the promastigote form of Leishmania major parasite (P) or Killed parasite (Kp) during a time course of infection [Balb/c]

(Submitter supplied) We analyzed the transcriptional signatures of mouse bone marrow-derived macrophages (BMDM) at different times after infection with promastigotes of the protozoan parasite Leishmania major. GeneChip Mouse Gene 1.0 ST arrays were used to analyse global changes in gene transcripts to generate a pool of genes that was statistically significant (p-value < 0.05) and a fold change cut-off of 1.5 in at least one of the five infected samples versus non-infected samples.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
48 Samples

Download data: CEL, TXT

Series

Accession:: GSE31995

ID:: 200031995

PubMed Full text in PMC Similar studies

Select item 2000702005.

Engagement of the Aryl Hydrocarbon Receptor in Mycobacterium tuberculosis–Infected Macrophages Has Pleiotropic Effects on Innate Immune Signaling

(Submitter supplied) Understanding the mechanisms of host macrophage responses to Mycobacterium tuberculosis (M.tb.) is essential for uncovering potential avenues of intervention to boost host resistance to infection. Macrophage transcriptome profiling revealed M.tb. infection strongly induced expression of several enzymes controlling tryptophan (Trp) catabolism. This included indole 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2), which catalyze the rate-limiting step in the kynurenine pathway, producing ligands for the aryl hydrocarbon receptor (AHR). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
8 Samples

Download data: CEL, XLSX

Series

Accession:: GSE70200

ID:: 200070200

Select item 2000637456.

MicroRNA expression profile in macrophages from rheumatoid arthritis and osteoarthritis patients

(Submitter supplied) In osteoarthritis (OA) and rheumatoid arthritis (RA), many pathological alterations result from aberrant macrophage hyperactivation in the inflamed synovial membrane, and inhibition of macrophage effector functions is a therapeutic strategy in both diseases. Little is known, about the specific genetic circuits that are differentially deregulated in RA and OA macrophages. microRNA (miR) are short single stranded non-coding RNAs involved in the post-transcriptional regulation of gene expression. more...

Organism:: Rattus norvegicus; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae