Similar studies for GEO DataSets (Select 200145761) - GEO DataSets

Select item 2001457611.

Different Egyptian rousette interferon omega proteins elicit an overlapping but not identical transcriptional response in bat cells.

(Submitter supplied) Abstract from accompanying publication: "Bats host a number of viruses that cause severe disease in humans without experiencing overt symptoms of disease themselves. While the mechanisms underlying this ability to avoid sickness are not known, deep sequencing studies of bat genomes have uncovered genetic adaptations that may have functional importance in the antiviral response of these animals. Egyptian rousette bats (Rousettus aegyptiacus) are the natural reservoir hosts of Marburg virus (MARV). more...

Organism:: Rousettus aegyptiacus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24487
66 Samples

Download data: TXT

Series

Accession:: GSE145761

ID:: 200145761

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001173672.

Infection of RoNi cells with Sendai Cantell virus, MARV371bat virus, and VP35 mutant MARV371bat-R301A virus at MOI of 1.0

(Submitter supplied) Study was performed in order to determine the scope of antiviral response of Rousettus aegyptiacus-derived fibroblasts to Sendai and Marburg virus infection. This study aids in understanding the function of the expanded immune repertoire of Rosettus aegyptiacus.

Organism:: Rousettus aegyptiacus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24487
36 Samples

Download data: GFF, H5

Series

Accession:: GSE117367

ID:: 200117367

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001089413.

Infection of RoNi cells with Sendai Cantell virus at MOI of 1.0

(Submitter supplied) Study was performed in order to determine the type and scope of interferon response of Rousettus aegyptiacus-derived fibroblasts to Sendai virus infection. This study helps to understand the function of the expanded immune repertoire of Rosettus aegyptiacus.

Organism:: Rousettus aegyptiacus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24487
18 Samples

Download data: GFF, H5

Series

Accession:: GSE108941

ID:: 200108941

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001022964.

Transcriptional response to type I IFN in bat P. alecto cells

(Submitter supplied) Bats are reservoirs of a number of highly pathogenic human viruses, yet they remain relatively asymptomatic during infection. Whether this viral resistance is due to a unique immune system is unknown. An evolutionarily conserved feature of vertebrate antiviral immunity is the interferon (IFN) response, which triggers cellular defenses through interferon-stimulated gene (ISG) expression. While bats encode an intact IFN system, global ISG expression patterns in bat cells are not well characterized. more...

Organism:: Pteropus alecto

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23872
15 Samples

Download data: TXT

Series

Accession:: GSE102296

ID:: 200102296

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001527285.

Infection of bats and cell cultures with Marburg, Ebola and Rabies viruses

(Submitter supplied) The response of bats to filoviral infections was studied to understand how they avoid getting sick

Organism:: Chiroptera

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28706
179 Samples

Download data: CSV, FA

Series

Accession:: GSE152728

ID:: 200152728

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001839256.

Landscape and age dynamics of immune cells in the Egyptian Rousette Bat

(Submitter supplied) Bats harbor high-impact zoonotic viruses in absence of clinical disease, which has been recently associated with unique features of their immune system. They seem to restrict inflammation and possibly limit disease manifestation to a minimum. In-depth characterization of cellular immunity in bats is yet largely missing, and imprinting of age and development on immune cell compartments remains unexplored. more...

Organism:: Rousettus aegyptiacus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL30616
4 Samples

Download data: MTX, TSV, TXT

Series

Accession:: GSE183925

ID:: 200183925

PubMed Similar studies SRA Run Selector

Select item 2000582877.

Transcriptional Profiling of the Immune Response to Marburg Infection

(Submitter supplied) Marburg virus is a genetically simple RNA virus that causes a severe hemorrhagic fever upon infection in humans and non-human primates. The mechanism of how this pathogenesis comes about is not well understood, but it is well accepted that pathogenesis is significantly driven by a hyperactive immune response. To better understand the overall response to Marburg virus challenge, we undertook a transcriptomic analysis of immune cells circulating in the blood following aerosol exposure of cynomolgus macaques to a lethal dose of Marburg virus. more...

Organism:: Homo sapiens; Macaca fascicularis

Type:: Expression profiling by array

Platform:: GPL10332
30 Samples

Download data: TXT

Series

Accession:: GSE58287

ID:: 200058287

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000417528.

Transcriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection

(Submitter supplied) Lassa fever virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with Lassa leads to the development of hemorrhagic fever in a significant number of public health cases and it is considered a potential bioweapon. Little is known about the complex immune mechanisms governing response to LASV infection, or the genetic determinants of susceptibility and resistance to infection. more...

Organism:: Macaca fascicularis; Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
30 Samples

Download data: TXT

Series

Accession:: GSE41752

ID:: 200041752

PubMed Full text in PMC Similar studies Analyze with GEO2R

GEO DataSets

Functional Genomics Studies

Result Filters

Entry type

Organism

Study type

Author

Attribute name

Publication dates

Custom date range

Additional filters

Send to:

Links from GEO DataSets

Items: 8

Send to:

Supplemental Content

Find related data

Important Links

Recent activity