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Links from GEO DataSets

Items: 4

1.

Amyotrophic Lateral Sclerosis Transcriptomics Reveals Immunological Effects of Low-Dose Interleukin-2.

(Submitter supplied) Neuroinflammation is one of the hallmarks of ALS. Regulatory T cells (Tregs) are immune-suppressive cells which physiologically regulate the immune system preventing the onset of autoimmune disorders. These cells are dramatically and progressive reduced in ALS patients, with lower levels correlated with shorter survival. Low-dose interleukin-2 (IL-2) has been roposed as an immune-modulatory strategy to boost Tres in ALS patient and to dampen neuroinflammation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL23126
107 Samples
Download data: CEL
Series
Accession:
GSE163560
ID:
200163560
2.

Establishing mRNA and microRNA interactions driving disease heterogeneity in Amyotrophic lateral sclerosis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL15456 GPL5175
120 Samples
Download data: CEL, CHP, TXT
Series
Accession:
GSE212134
ID:
200212134
3.

Establishing mRNA and miRNA interactions driving disease heterogeneity in ALS patient survival (miRNA-Seq)

(Submitter supplied) Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, associated with the degeneration of both upper and lower motor neurons of the motor cortex, brainstem and spinal cord. Death in most patients results from respiratory failure within 3-4 years from symptom onset. However, due to disease heterogeneity some individuals survive only months from symptom onset while others live for several years. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL15456
78 Samples
Download data: TXT
Series
Accession:
GSE212133
ID:
200212133
4.

Establishing mRNA and miRNA interactions driving disease heterogeneity in ALS patient survival (microarray)

(Submitter supplied) Transcriptomic analysis of lymphoblastoid cell lines from ALS patients with varying disease duration Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, associated with the degeneration of both upper and lower motor neurons of the motor cortex, brainstem and spinal cord. Death in most patients results from respiratory failure within 3-4 years from symptom onset. However, due to disease heterogeneity some individuals survive only months from symptom onset while others live for several years. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5175
42 Samples
Download data: CEL, CHP
Series
Accession:
GSE212131
ID:
200212131
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