GEO DataSets

(Submitter supplied) Background: Of the many neurotransmitters in humans, gamma-aminobutyric acid (GABA) shows potential for improving several mental health indications such as stress and anxiety. The microbiota-gut-brain axis is an important pathway for GABAergic effects, as microbially-secreted GABA within the gut can affect host mental functionhealth outcomes. Understanding the molecular characteristics of GABA production by microbes within the gut can offer insight to novel therapies for mental health. more...

Organism:

Levilactobacillus brevis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30477

40 Samples

Download data: CSV, GFF

(Submitter supplied) Purpose: High γ-aminobutyric acid (GABA)-producing Levilactobacillus brevis strain NPS-QW 145 along with Streptococcus thermophilus (one of the two starter bacteria used to make yogurt for its proteolytic activity) to enhance GABA production in milk. But a mechanistic understanding on how Levilactobacillus brevis cooperated with S. thermophilus to stimulate GABA production has been lacking. Method: Metatranscriptomic analyses combined with peptidomics were carried out to unravel the casein and lactose utilization patterns during milk fermentation with the co-culture. more...

Organism:

Levilactobacillus brevis; Streptococcus thermophilus ASCC 1275

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL29153 GPL29152

6 Samples

Download data: FA, TXT