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Single-cell RNA-seq analysis of cells from degenerating and non-degenerating intervertebral discs from the same individual reveals new biomarkers for intervertebral disc degeneration
PubMed Full text in PMC Similar studies
Single-Cell RNA-Sequencing Atlas of Bovine Caudal Intervertebral Discs: Discovery of Heterogeneous Cell Populations with Distinct Roles in Homeostasis
PubMed Full text in PMC Similar studies SRA Run Selector
Intervertebral disc degeneration
Shared and compartment-specific processes in nucleus pulposus and annulus fibrosus during intervertebral disc degeneration
The cellular landscape of the healthy human intervertebral disc: identification of new immature cell populations and their relationship with mature populations at single cell resolution
Transcriptional profiling of human cartilage endplate cells identified novel genes and cell clusters underlying degenerated and non-degenerated phenotypes (scRNA-seq)
Transcriptional profiling of human cartilage endplate cells identified novel genes and cell clusters underlying degenerated and non-degenerated phenotypes
bulk RNA-seq of human nucleusus pulposus from disc-degenerated patients
PubMed Similar studies
Tagln+ progenitors contribute to the development and maintenance of nucleus pulposus
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Genome-wide DNA methylation profile analysis of human intervertebral disc degeneration
Gene expression profile at single cell level of nucleus pulposus cells (NPCs) from the nucleus pulposus (NP) tissue in the mild degenerative intervertebral discs (MDD) and server degenerative intervertebral discs(SDD).
Me-RIP- Sequencing Analysis of normal and senescent nucleus pulposus cells Transcriptomes
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
Next Generation Sequencing analysis at single-cell level of normal and degenerated nucleus pulposus cells transcriptomes
Single Cell RNA Sequencing of Adult Mouse Intervertebral Disc Cells
Transcriptome analysis of CHSY3 knockdown NP cells
Sox9 Deletion Causes Severe Intervertebral Disc Degeneration Characterized by Apoptosis, Matrix Remodeling, and Compartment-Specific Transcriptomic Changes
PubMed Full text in PMC Similar studies Analyze with GEO2R
Gene Array Data from Human Annulus Disc Tissue
Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration
Human iPS cell-derived cartilage spatially and functionally replaces nucleus pulposus
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