Similar studies for GEO DataSets (Select 200217991) - GEO DataSets

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Items: 6

Select item 2002179911.

Chimeric RNA RRM2-C2orf48 plays an oncogenic role in the development of NNK-induced lung cancer

(Submitter supplied) Chimeric RNAs have been used as biomarkers and therapeutic targets for multiple types of cancers. However, less attention has been paid to their mechanism of action in neoplasia. Here, we report that chimeric RNA RRM2-C2orf48 promotes 4-(methyl nitrosamine)-1-(3-pyridinyl)-1-butanone (NNK)-induced lung cancer. We found that RRM2-C2orf48 had higher expression levels in lung cancer cell lines and in lung cancer tissues from 74 patients than in normal cells and tissues, respectively. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
6 Samples

Download data: XLSX

Series

Accession:: GSE217991

ID:: 200217991

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001001932.

Novel chimeric transcript RRM2-c2orf48 promotes metastasis in nasopharyngeal carcinoma

(Submitter supplied) A microarray analysis was performed on the vector and over-expressing RRM2-c2orf48 NPC cell samples(CNE2-PMSCV-Vector and CNE2-PMSCV-RRM2-c2orf48). Total RNA was extracted from 1 × 106 cells using TRIzol reagent and was further purified using a Qiagen RNeasy Mini Kit according to the manufactures’ instructions. RNA quality was assessed by formaldehyde agarose gel electrophoresis and was quantitated spectrophotometrically. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
2 Samples

Download data: CEL

Series

Accession:: GSE100193

ID:: 200100193

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001179243.

RNA sequencing of RRM2 knockdown in C4-2 cells

(Submitter supplied) Human prostate cancer C4-2 cells transfected with siRNAs (siNS and siRRM2). Knockdown were confirm by westernblot or qPCR. Transfected cells were prepared for RNA-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: XLSX

Series

Accession:: GSE117924

ID:: 200117924

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001179234.

RNA sequencing of RRM2 overexpressing in PC-3 cells

(Submitter supplied) Human prostate cancer PC-3 cells stably overexpress RRM2. Overexpression of RRM2 were confirm by westernblot or qPCR. Transfected cells were prepared for RNA-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: XLSX

Series

Accession:: GSE117923

ID:: 200117923

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001179225.

RNA sequencing of RRM2 overexpressing in LNCaP cells

(Submitter supplied) Human prostate cancer LNCaP cells stably overexpress RRM2. Overexpression of RRM2 were confirm by westernblot or qPCR. Transfected cells were prepared for RNA-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: XLSX

Series

Accession:: GSE117922

ID:: 200117922

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001179216.

RNA sequencing of COH29 treatment in C4-2 cells

(Submitter supplied) Human prostate cancer C4-2 cells treated with COH29 and DMSO. Cells were treated with DMSO, 10uM or 20 uM COH29 for 48 hours. Cells were prepared for RNA-seq.