GEO DataSets

Analysis of microvascular endothelial cells stimulated to either proliferate or undergo tubulogenesis in vitro. Results provide insight into the molecular mechanisms underlying the regulation of endothelial cell morphogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol, 6 time sets

Platform:

GPL97

Series:

GSE3891

10 Samples

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(Submitter supplied) Human microvascular endothelial cells were stimulated to either proliferate or undergo tubulogenesis over an 8 hour time period. Keywords: Time Series

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS2039 GDS2040

Platforms:

GPL97 GPL96

20 Samples

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Analysis of microvascular endothelial cells stimulated to either proliferate or undergo tubulogenesis in vitro. Results provide insight into the molecular mechanisms underlying the regulation of endothelial cell morphogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol, 6 time sets

Platform:

GPL96

Series:

GSE3891

10 Samples

Download data

(Submitter supplied) The pathogenesis of endometriosis may result from aberrant angiogenesis that occurs in eutopic endometrium with retrograde menstruation. The difference in gene expression profile between human endometrial endothelial cells (HEECs) from eutopic endometria of patients with and without endometriosis would be determinant that affects the occurrence of endometriosis. To explore this kind of difference, we performed in vitro culture and identified their endothelial origin, as well as observed growth features of HEECs from the two different origins. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3060

Platform:

GPL570

10 Samples

Download data: CEL

Analysis of cultured endometrial endothelial cells derived from the eutopic endometria of patients with endometriosis. Results provide insight into the role of aberrant angiogenesis in the pathogenesis of endometriosis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL570

Series:

GSE7846

10 Samples

Download data: CEL

(Submitter supplied) Little is known about the pan-microvascular transcriptome, particularly considering gene transcripts and their encoded proteins that can be considered as vascular-selective in their expression. Using a combination of publicly available and our own transcript profiles, we identified a core set of gene transcripts, which are specifically and broadly expressed in the microvasculature. Keywords: cell type comparison, developmental regulation

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

9 Samples

Download data: CEL

(Submitter supplied) This is a time course experiment with 4 - 6 slides per time point where all samples were hybridised to time zero. The microarray slides were scanned using a GenePix 4000B Scanner (Axon Instruments, Foster City, CA, USA). The “SPOT” software package (CSIRO) was used to identify spots and subtract backgrounds. The extracted information was normalised using the “Statistics in Microarray Analysis" (SMA) open source R package. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL555

18 Samples

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(Submitter supplied) To compare the gene expression profiles of unpassaged, proliferating HUVEC and human iris, retinal and choroidal microvascular endothelial cells. Gene expression profiling revealed significant differences between HUVEC and ocular microvascular endothelial cells suggesting that HUVE cells may not be a suitable surrogate when studying pathophysiological mechanisms of ocular disorders. There were significant differences in the gene expression of important cell signalling pathways in human retinal and choroidal ECs. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

12 Samples

Download data: CEL

(Submitter supplied) We generated the transcriptional regulatory footprint of phthalimide neovascular factor 1 (PNF1)—a novel synthetic small molecule that exhibits significant in vitro endothelial potency and significant in vivo microvascular network expansion—by performing comparative microarray analysis on PNF1-stimulated (versus control) human microvascular endothelial cells (HMVEC) spanning 1-48 h post-supplementation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

14 Samples

Download data: CEL