Similar studies for GEO DataSets (Select 2287) - GEO DataSets

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Items: 20

Select item 22871.

Airway epithelial cell response to Pseudomonas aeruginosa rsmA mutant infection

Analysis of airway epithelial cells infected with Pseudomonas aeruginosa PAO1 or the rsmA mutant. RsmA is a small RNA-binding protein that plays a role in the regulation of virulence-related genes in P. aeruginosa. Results provide insight into the influence of RsmA-regulated functions on the host.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 genotype/variation, 2 infection sets

Platform:: GPL96
Series:: GSE4485
6 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2287

ID:: 2287

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000044852.

Global expression profiling of airway epithelial cells infected with Pseudomonas aeruginosa and the rsmA mutant

(Submitter supplied) Global expression profiling of airway epithelial cells infected with Pseudomonas aeruginosa and the rsmA mutant. Recent work in our laboratory investigated the impact of RsmA on a number of airway epithelial cell phenotypes including actin depolymerization, cytotoxicity and invasion. These cellular phenotypes were influenced by the positive effect of RsmA on the expression of the TTSS in P. aeruginosa (Mulcahy et al. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2287
Platform:: GPL96
6 Samples

Download data: CEL, EXP

Series

Accession:: GSE4485

ID:: 200004485

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000020563.

PBECs stimulated with pro-inflammatory cytokines and P. aeruginosa

(Submitter supplied) Comparison of libraries derived from primary human bronchial epithelial cells which are [i] unstimulated, [ii] stimulated with the pro-inflammatory cytokines IL1beta and TNFalpha and [iii] stimulated with heat-inactivated Pseudomonas aeruginosa (strain PAO1). Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL4
3 Samples

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Series

Accession:: GSE2056

ID:: 200002056

PubMed Similar studies

Select item 2000014694.

A549 lung pneumocytes cell line infected with wildtype and deletion mutation PAK strain Pseudomonas aeruginosa

(Submitter supplied) The bacterial type III secretion system (TTSS) is dedicated to directly effect host cell pathways by pathogens. In order to identify the key host responses of the various parts of the TTSS, we utilized expression profiling of a lung pneumocytes cell line, A549, exposed to various isogenic mutant strains of Pseudomonas aeruginosa PAK. We have devised a novel filtering method to isolate the key responses to the effector proteins as well as the translocation machinery. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1022
Platform:: GPL8300
16 Samples

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Series

Accession:: GSE1469

ID:: 200001469

Select item 10225.

Lung pneumocyte response to Pseudomonas aeruginosa type III secretion system mutants

Analysis of A549 lung pneumocytes after infection with Pseudomonas aeruginosa (PA) PAK mutants deleted for various components of the type III secretion system (TTSS). Mutants in TTSS effectors and translocators studied. PA causes serious respiratory infections in cystic fibrosis patients.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 7 genotype/variation, 2 infection sets

Platform:: GPL8300
Series:: GSE1469
16 Samples

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DataSet

Accession:: GDS1022

ID:: 1022

Select item 2000086186.

P. aeruginosa virulent factor to barley

(Submitter supplied) To identify the difference of gene expression in barley upon P. aeruginosa PAO1 and less pathogenic PA5021 mutant Keywords: Disease response

Organism:: Hordeum vulgare

Type:: Expression profiling by array

Platform:: GPL1340
3 Samples

Download data: CEL

Series

Accession:: GSE8618

ID:: 200008618

Select item 2000046147.

The Influence of Human Respiratory Epithelia on Pseudomonas aeruginosa Gene Expression

(Submitter supplied) To gain insights into the initial phases of P. aeruginosa infections and to identify P. aeruginosa genes regulated in response to respiratory epithelia we exposed P. aeruginosa to cultured primary differentiated human airway epithelia. We used a P. aeruginosa strain (PAO1) that causes acute damage to the epithelia and a mutant (PAOSC11) with defects in Type III secretion and in rhamnolipid synthesis. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS2502
Platform:: GPL84
8 Samples

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Series

Accession:: GSE4614

ID:: 200004614

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 25028.

Pseudomonas aeruginosa response to airway epithelia

Analysis of Pseudomonas aeruginosa PAO1 or Type III secretion system (TTSS), rhamnolipid synthesis double mutant strain exposed to cultured airway epithelia. TTSS is a virulence factor in acute infections. Strains from chronic infections express decreased levels of TTSS or lack a functional TTSS.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, count, 2 agent, 2 strain sets

Platform:: GPL84
Series:: GSE4614
8 Samples

Download data

DataSet

Accession:: GDS2502

ID:: 2502

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000084089.

Transcriptomic analysis of the sulfate starvation response in Pseudomonas aeruginosa

(Submitter supplied) Gene expression in response to changes in sulfur supply was studied in P. aeruginosa E601, a cystic fibrosis isolate that displays mucin sulfatase activity, and in P. aeruginosa PAO1. A large family of genes was found to be upregulated by sulfate limitation in both isolates, encoding sulfatases and sulfonatases, transport systems, oxidative stress proteins, and a sulfate-regulated TonB/ExbBD complex. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS2870
Platform:: GPL84
20 Samples

Download data: CEL

Series

Accession:: GSE8408

ID:: 200008408

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 287010.

Pseudomonas aeruginosa cystic fibrosis isolate response to various sulfur sources

Analysis of Pseudomonas aeruginosa E601 grown in media containing various sources of sulfur. P. aeruginosa E601 is a cystic fibrosis isolate that exhibits mucin sulfatase activity. Results provide insight into the pathways that respond to the nature of the supply of sulfur.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, transformed count, 5 growth protocol, 2 strain sets

Platform:: GPL84
Series:: GSE8408
20 Samples

Download data: CEL

DataSet

Accession:: GDS2870

ID:: 2870

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20000309011.

Microarray Analysis of Pseudomonas aeruginosa Reveals Induction of Pyocin Genes in Response to Hydrogen Peroxide

(Submitter supplied) Background: Pseudomonas aeruginosa, a pathogen infecting those with cystic fibrosis, encounters toxicity from phagocyte-derived reactive oxidants including hydrogen peroxide during active infection. P. aeruginosa responds with adaptive and protective strategies against these toxic species to effectively infect humans. Despite advances in our understanding of the responses to oxidative stress in many specific cases, the connectivity between targeted protective genes and the rest of cell metabolism remains obscure. more...

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1

Type:: Expression profiling by array

Dataset:: GDS1469
Platform:: GPL84
9 Samples

Download data

Series

Accession:: GSE3090

ID:: 200003090

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 146912.

Oxidative stress effect on pyocin expression

Expression profiling of strain PA01 exposed to hydrogen peroxide, a reactive oxygen species, at a sublethal concentration of 1 mM. Results identify upregulation of pyocin (bacteriocin) genes as a potentially novel defensive scheme in response to oxidative attack by infected host cells.

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL84
Series:: GSE3090
9 Samples

Download data

DataSet

Accession:: GDS1469

ID:: 1469

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20001060413.

Microarray Analysis of Toxicogenomic Effects of Ortho-Phenylphenol on Pseudomonas aeruginosa

(Submitter supplied) In the present study, we employed Affymetrix Pseudomonas aeruginosa GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Pseudomonas aeruginosa to ortho-phenylphenol, which involved initial growth inhibition and metabolism. Keywords: Time course

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
12 Samples

Download data: CEL

Series

Accession:: GSE10604

ID:: 200010604

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000972314.

Gingival Epithelial Cell Transcriptional Responses to Pathogenic Oral Microbial Species.

(Submitter supplied) Transcriptional profiling was utilized to define the biological pathways of gingival epithelial cells modulated by co-culture with the oral pathogenic Porphyromonas gingivalis and Aggregatibacter (formerly actinobacillus) actinomycetemcomitans. We used microarrays to detail the global programme of gene expression underlying infection and identified distinct classes of up- and down-regulated genes during this process. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3211
Platform:: GPL96
12 Samples

Download data: CEL

Series

Accession:: GSE9723

ID:: 200009723

Select item 321115.

Gingival epithelial cell line response to oral pathogen infections

Analysis of gingival epithelial HIGK cells infected with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis. A. actinomycetemcomitans and P. gingivalis cause periodontal infections. Results provide insight into differences in epithelial cell responses to these pathogens.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 infection sets

Platform:: GPL96
Series:: GSE9723
12 Samples

Download data: CEL

DataSet

Accession:: GDS3211

ID:: 3211

Select item 20000185316.

interaction with bacteria or bacterial supernatant

(Submitter supplied) Epithelial cells were in contact either with live bacteria (S. aureus) or with bacterial supernatant during 3 hours. Three dependant experiment for each condition were performed. RNA from epithelial cells were extracted. Each condition was hybridized on 6 slides (3 slides with their corresponding swap) Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1521
12 Samples

Download data

Series

Accession:: GSE1853

ID:: 200001853

Select item 20000170417.

Epithelial cells in contact with bacterial supernatant

(Submitter supplied) Epithelial cells were in contact with bacteria supernatant during different times of incubation. time course supernatant 10 % MM39 Keywords: time-course

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1417
5 Samples

Download data

Series

Accession:: GSE1704

ID:: 200001704

Select item 20013833818.

Widespread targeting of nascent transcripts by RsmA in Pseudomonas aeruginosa

(Submitter supplied) In the opportunistic pathogen Pseudomonas aeruginosa RsmA is an RNA-binding protein that plays critical roles in the control of virulence, interbacterial interactions and biofilm formation. Although RsmA is thought to exert its regulatory effects by binding full-length transcripts, the extent to which RsmA binds nascent transcripts has not been addressed. Moreover, which transcripts are direct targets of this key post-transcriptional regulator is largely unknown. more...

Organism:: Pseudomonas aeruginosa PAO1

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL23999 GPL18782
30 Samples

Download data: BED, BW, TXT, WIG

Series

Accession:: GSE138338

ID:: 200138338

PubMed Full text in PMC Similar studies

Select item 20001154419.

Expression data from Pseudomonas aeruginosa infiltrated into resistant and susceptible cultivars of Nicotiana tabacum.

(Submitter supplied) Although Pseudomonas aeruginosa is an opportunistic pathogen that does not often naturally infect alternate hosts such as plants, the plant-P. aeruginosa model has become a widely recognized system for identifying new virulence determinants and studying pathogenesis of this organism. Here we examine how both host factors and P. aeruginosa PAO1 gene expression are affected in planta after infiltration into incompatible and compatible cultivars of tobacco (Nicotiana tabacum L.) Nicotiana tabacum has a resistance gene (N) against tobacco mosaic virus; and although resistance to PAO1 infection correlated to the presence of a dominant N-gene, our data suggests that it is not a factor in resistance against Pseudomonas. more...

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1

Type:: Expression profiling by array

Platform:: GPL84
6 Samples

Download data: CEL

Series

Accession:: GSE11544

ID:: 200011544

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005140920.

PAO1 gene expression at 22°C and 37°C in Lysogeny broth

(Submitter supplied) Pseudomonas aeruginosa strain PAO1 was grown at 22°C and 37°C in Lysogeny broth (LB) and RNA was hybridized on the Affymetrix P. aeruginosa chip.

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1

Type:: Expression profiling by array

Platform:: GPL84
6 Samples

Download data: CEL, TXT

Series

Accession:: GSE51409

ID:: 200051409

PubMed Full text in PMC Similar studies Analyze with GEO2R

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