GEO DataSets

Analysis of baseline non-small cell lung cancer (NSCLC) cell lines with a broad range of sensitivity to the anticancer drug gefitinib. Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). Results used to define a gene expression signature of gefitinib sensitivity.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 18 cell line, 3 other, 2 protocol sets

Platform:

GPL97

Series:

GSE4342

18 Samples

Download data

(Submitter supplied) Eleven NSCLC cell lines with widely divergent gefitinib sensitivities were compared using gene expression. Genes associated with gefitinib response were used to classify additional NSCLC lines with unknown gefitnib sensitivity. A subset of the test set data was tested for gefitinib sensitivity, and results correlated strongly with the gene expression-based predictions All eleven training set lines, and seven test set lines had both HGU133A and B chips done, while other test set lines had only HGU133As. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS2297 GDS2298

Platforms:

GPL97 GPL96

63 Samples

Download data

Analysis of baseline non-small cell lung cancer (NSCLC) cell lines with a broad range of sensitivity to the anticancer drug gefitinib. Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). Results used to define a gene expression signature of gefitinib sensitivity.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 41 cell line, 4 other, 2 protocol sets

Platform:

GPL96

Series:

GSE4342

45 Samples

Download data

(Submitter supplied) Global gene expression data were generated from cultured non small cell lung cancer cell lines (NSCLC), normalized using MAS 5.0, filtered and used to predict response of cells to EGFR inhibition

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

48 Samples

Download data: CEL