Similar studies for GEO DataSets (Select 3215) - GEO DataSets

Select item 32151.

13-cis retinoic acid effect on SEB-1 sebocyte cell line

Analysis of cultured sebaceous gland cells (SEB-1 sebocytes) treated with 13-cis retinoic acid (13-cis RA, isotretinoin), a potent acne treatment agent that reduces the size and secretion of sebaceous glands. Results provide insight into the molecular basis for 13-cis RA's acne-clearing effect.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL8300
Series:: GSE10432
6 Samples

Download data: CEL

DataSet

Accession:: GDS3215

ID:: 3215

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000104342.

Retinoic acid effect on sebocytes and the skin

(Submitter supplied) The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. 13-cis Retinoic Acid (13-cis RA, isotretinoin) is the most potent agent in acne treatment. Surprisingly, its mechanism of action in acne is still unknown. Gene expression profiling of cultured human immortalized sebocytes (SEB-1) treated with 13-cis RA was performed to gain insights into its sebocyte-specific mechanism of action. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL571 GPL8300
18 Samples

Download data: CEL

Series

Accession:: GSE10434

ID:: 200010434

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000104333.

Human Skin: Before and 1 week after Isotretinoin Treatment

(Submitter supplied) The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. 13-cis Retinoic Acid (13-cis RA, isotretinoin) is the most potent agent in acne treatment. Surprisingly, its mechanism of action in acne is still unknown. Gene expression profiling of skin from 6 patients treated with isotretinoin was performed to gain insights into its mechanism of action. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3218
Platform:: GPL571
12 Samples

Download data: CEL

Series

Accession:: GSE10433

ID:: 200010433

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000104324.

13-cis retinoic acid treatment of human sebocytes (SEB-1)

(Submitter supplied) The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. 13-cis Retinoic Acid (13-cis RA, isotretinoin) is the most potent agent in acne treatment. Surprisingly, its mechanism of action in acne is still unknown. Gene expression profiling of cultured human immortalized sebocytes (SEB-1) treated with 13-cis RA was performed to gain insights into its sebocyte-specific mechanism of action. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3215
Platform:: GPL8300
6 Samples

Download data: CEL

Series

Accession:: GSE10432

ID:: 200010432

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 32185.

13-cis retinoic acid effect on skin

Analysis of upper back skin biopsies of acne patients treated with 13-cis retinoic acid (13-cis RA, isotretinoin), a potent acne treatment agent that reduces the size and secretion of sebaceous glands. Results provide insight into the molecular basis for 13-cis RA's acne-clearing effect.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 6 individual sets

Platform:: GPL571
Series:: GSE10433
12 Samples

Download data: CEL

DataSet

Accession:: GDS3218

ID:: 3218

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000242436.

Murine skin gene expression analysis of skin-specific Scd1-deficient and control mice

(Submitter supplied) To help elucidate the metabolic changes in the skin that contribute to the obesity resistance and skin pathology in mice lacking Scd1, we performed microarray analysis of skin gene expression in male skin Scd1 knockout (SKO) and Scd1 flox/flox control (Lox) mice fed a standard rodent diet. We identified an extraordinary number of differentially expressed genes that support the previously documented histological observations of sebocyte atrophy, inflammation and epidermal hyperplasia in SKO mice. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4910
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE24243

ID:: 200024243

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49107.

Stearoyl-CoA desaturase-1 deficiency effect on the skin

Analysis of skins of animals with skin-specific deletion of Scd1. Animals with skin-specific deletion of Scd1 develop severe sebaceous gland hypoplasia that results in progressive scarring alopecia. Results provide insight into the molecular basis of Scd1-deficient skin pathology

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE24243
6 Samples

Download data: CEL

DataSet

Accession:: GDS4910

ID:: 4910

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000117928.

Human Skin: Before and 8 weeks after Isotretinoin Treatment

(Submitter supplied) The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. 13-cis Retinoic Acid (13-cis RA, isotretinoin) is the most potent agent in acne treatment. Surprisingly, its mechanism of action in acne is still unknown. Gene expression profiling of skin from 8 patients treated with isotretinoin was performed to gain insights into its mechanism of action. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL571
16 Samples

Download data: CEL

Series

Accession:: GSE11792

ID:: 200011792

PubMed Full text in PMC Similar studies Analyze with GEO2R

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