Similar studies for GEO DataSets (Select 3298) - GEO DataSets

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Items: 4

Select item 32981.

Peripheral blood monocyte response to Francisella tularensis infections

Analysis of blood monocytes infected with Francisella tularensis tularensis Schu S4 (virulent) or subsp. novicida (less virulent). F. tularensis causes the disease tularemia. Results provide insight into the molecular mechanisms that enable Francisella to dampen or subvert the host immune response.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 infection sets

Platform:: GPL570
Series:: GSE12108
14 Samples

Download data: CEL

DataSet

Accession:: GDS3298

ID:: 3298

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000121082.

Microarray analysis of human monocytes infected with Francisella tularensis

(Submitter supplied) Differential expression in human peripheral blood monocytes between F. novicida-infected and uninfected, and between Francisella tularensis tularensis isolate Schu S4 and uninfected. The goal was to examine genomewide transcriptional reponses to these two strains, and identify differentially-regulated genes that may help explain the virulence of Schu S4. Keywords: Immune Response, Human Monocytes, Bacteria, Francisella

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3298
Platform:: GPL570
14 Samples

Download data: CEL

Series

Accession:: GSE12108

ID:: 200012108

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000684783.

Expression data from multiple strains of Francisella

(Submitter supplied) Comparison of expression profiles of strains of Francisella to identify virulence factors We used custom microarrays to detail the global gene expression of four strains of Francisella (Schu4, LVS, OR960246, U112) and identified distinct classes of differentially expressed genes during this process.

Organism:: Francisella tularensis subsp. holarctica LVS; Francisella tularensis subsp. holarctica OR96246; Francisella tularensis subsp. tularensis SCHU S4; Francisella; Francisella tularensis subsp. novicida U112

Type:: Expression profiling by array

Platform:: GPL20119
12 Samples

Download data: CEL

Series

Accession:: GSE68478

ID:: 200068478

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000658714.

Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized TLR4 agonist

(Submitter supplied) Prior aerosol exposure to F. tularensis subsp. tularensis, but not the live attenuated strain (LVS) of F. tularensis subsp. holarctica or F. novicida, significantly antagonized the transcriptional response in the lungs of infected mice exposed to aerosolized TLR4 ligand E. coli LPS.