Similar studies for GEO DataSets (Select 3428) - GEO DataSets

Select item 34281.

Immature dendritic cell response to butanol fraction of Echinacea purpurea: time course

Analysis of immature dendritic cell lines (iDCs) treated with the butanol-fraction of stems and leaves of E. purpurea [BF/S+L/Ep] containing defined bioactive phytocompounds. Results provide insight into molecular mechanisms underlying the immune-modulatory activities induced by the phytocompounds.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 agent, 4 time sets

Platform:: GPL96
Series:: GSE12259
9 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3428

ID:: 3428

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000122592.

Human dendritic cells treated with Echinacea purpurea phytocompounds

(Submitter supplied) This study investigated the specific and differential gene expression in human immature DCs (iDCs) in response to treatment with a butanol fraction containing defined bioactive phytocompounds extracted from stems and leaves of Echinacea purpurea

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3428
Platform:: GPL96
9 Samples

Download data: CEL, CHP

Series

Accession:: GSE12259

ID:: 200012259

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000150893.

Time-course of gene expression in BMDCs stimulated with gamma-PGA nanoparticles

(Submitter supplied) The gene expression levels in murine bone marrow-derived dendritic cells treated with γ-PGA NPs were examined by oligonucleitide microarray at 6, 12 and 24 hours. The gene expression of proinflammatory chemokines, cytokines, and costimulatory molecules was upregulated considerably in DCs treated with γ-PGA NPs at 6 hours.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
12 Samples

Download data: TXT

Series

Accession:: GSE15089

ID:: 200015089

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000150874.

Comparison of gene expression in BMDCs stimulated with gamma-PGA nanoparticles, LPS and unparticulate gamma-PGA

(Submitter supplied) The gene expression levels in murine bone marrow-derived dendritic cells treated with γ-PGA NPs were examined by oligonucleitide microarray and compared with those in the cells treated with other adjuvants. The gene expression of proinflammatory chemokines, cytokines, and costimulatory molecules was upregulated considerably in DCs treated with γ-PGA NPs. The upregulation pattern was similar to that in DCs treated with LPS but not in DCs treated with unparticulate γ-PGA. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
12 Samples

Download data: TXT

Series

Accession:: GSE15087

ID:: 200015087

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000068635.

Immature dendritic cells under hypoxic condition

(Submitter supplied) Dendritic cells (DCs) are professional antigen-presenting cells whose activity is intrinsically linked to the microenvironment. Hypoxia is a condition of low oxygen tension occurring in inflammatory tissues that creates a special microenvironment conditioning cell physiology. We studied the effects of hypoxia on the differentiation of human monocytes into DCs. Immature DCs were differentiated in vitro from human monocytes under normoxic (iDCs) or hypoxic (Hi-DCs) conditions and the gene expression profile was determined. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2750
Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE6863

ID:: 200006863

Select item 27506.

Immature dendritic cell response to hypoxia in vitro

Analysis of immature dendritic cells (DCs) differentiated from monocytes under hypoxia for 4 days. DCs are antigen presenting cells whose development is influenced by the microenvironment. Hypoxia is an important constituent of the microenvironment of inflamed tissues.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 stress sets

Platform:: GPL570
Series:: GSE6863
6 Samples

Download data: CEL

DataSet

Accession:: GDS2750

ID:: 2750

Select item 2001179047.

Echinacea purpurea elicits anti-viral response in THP-1 monocytes through activation of interferon, MAPK and NF-κB signaling pathways and DNA hypermethylation of repeat elements

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by genome tiling array

Platforms:: GPL21145 GPL10558
24 Samples

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Series

Accession:: GSE117904

ID:: 200117904

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001179038.

DNA methylation profiles of THP1 monocyte cells following Echinaforce treatment

(Submitter supplied) Until today, natural Echinacea purpurea extracts are widely used to prevent and treat respiratory trac infections. Although its immunomodulatory effects have already been demonstrated by several studies, the molecular mechanisms involved are not yet completely understood. In this study, we applied a systems biology approach by integrating transcriptome, kinome and methylome profiles of THP-1 monocyte cells treated with Echinaforce®, a commercial standardized ethanolic tincture of Echinacea purpurea. more...