Similar studies for GEO DataSets (Select 3507) - GEO DataSets

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Items: 4

Select item 35071.

Spinal cord injury effect on the urinary bladder: time course

Analysis of bladders from Sprague-Dawley females for up to 25 days following spinal cord injury (SCI). Bladder wall tissue compliance increases within 2 weeks after SCI in this animal model. Results provide insight into the molecular basis of the changes that the bladder undergoes after SCI.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 disease state, 4 time sets

Platform:: GPL85
Series:: GSE14096
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3507

ID:: 3507

Select item 2000140962.

Urinary bladder post-spinal cord injury: time-points

(Submitter supplied) Previously, we demonstrated using a rat model of spinal cord injury (SCI) that bladder wall tissue compliance significantly increased within the first 2 weeks following injury. In order to explore the potential molecular-level mechanisms of this event, the present study quantified molecules pertinent to bladder tissue remodeling and changes in mechanical properties. An initial gene array analysis followed by real-time qPCR revealed that the message levels for tropoelastin and lysyl oxidase were as high as 8-fold in SCI rats compared to normal. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3507
Platform:: GPL85
4 Samples

Download data: CEL, CHP

Series

Accession:: GSE14096

ID:: 200014096

Select item 2000025993.

Chronic contusion spinal cord injury in rats

(Submitter supplied) Excerpt from a larger study which characterized the transcriptional effects of a spinal cord contusion injury in rats. This is the data from the almost chronic contusion state (35 days) at the injury site (Thoracic 8) - where we saw significant changes in several areas, including cholesterol metabolism genes. Other spinal cord areas (rostral, caudal) and time-points (3 hours, 24 hours, 7 days and 35 days) were analyzed as well and are discussed in our paper and at www.crpf.org/microarray. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1238
Platform:: GPL85
6 Samples

Download data

Series

Accession:: GSE2599

ID:: 200002599

Select item 12384.

Spinal cord contusion

Expression profiling of contused spinal cords of Fischer animals. Spinal cords examined 35 days following contusion at the thoracic 8 segment. Results identify potential targets for therapeutic intervention following spinal cord injury.