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Links from GEO DataSets

Items: 2

1.
Full record GDS3529

Pancreatic islet response to glucose in vitro: dose response

Analysis of pancreatic islets cultured for 18 hours in 2, 5, 10, or 30 mM glucose. Culture in 2 to 10 mM glucose improves beta cell survival and function, while concentrations above 10 mM are deleterious. Results provide insight into the molecular basis of this sensitivity to glucose concentrations.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 dose sets
Platform:
GPL1355
Series:
GSE12817
16 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3529
ID:
3529

PubMed Similar studies GEO Profiles Analyze DataSet

2.

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low, intermediate and high [glucose]

(Submitter supplied) Background: Survival and function of insulin-secreting pancreatic β-cells are markedly altered by changes in nutrient availability. In vitro, culture in 10 rather than 2mM glucose improves rodent β-cell survival and function whereas glucose concentrations above 10mM are deleterious. Aim-Method: To identify the mechanisms of such β-cell plasticity, we tested the effects of a 18h culture at 2, 5, 10 and 30mM glucose on the transcriptome of rat islets precultured for 1 week at 10mM glucose (Affymetrix Rat 230.2 arrays). more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3529
Platform:
GPL1355
16 Samples
Download data: CEL, EXP
Series
Accession:
GSE12817
ID:
200012817

PubMed Similar studies Analyze with GEO2R

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