Similar studies for GEO DataSets (Select 3560) - GEO DataSets

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Items: 20

Select item 35601.

Occupational benzene exposure: peripheral blood mononuclear cells (HG-U133B)

Analysis of peripheral blood mononuclear cells from shoe factory workers exposed to benzene. Benzene is a leukemogen. Results provide insight into molecular mechanisms of benzene carcinogenicity.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL97
Series:: GSE9569
16 Samples

Download data: CEL

DataSet

Accession:: GDS3560

ID:: 3560

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000095692.

Gene expression in benzene-exposed workers

(Submitter supplied) The effect of benzene exposure on peripheral blood mononuclear cell (PBMC) gene expression was examined in a population of shoe-factory workers with well-characterized occupational exposures to benzene. We compared data from two microarray platforms (Illumina and Affymetrix). Keywords: occupational exposure

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS3559 GDS3560 GDS3561
Platforms:: GPL96 GPL97 GPL2700
48 Samples

Download data: CEL, XLS

Series

Accession:: GSE9569

ID:: 200009569

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Select item 35613.

Occupational benzene exposure: peripheral blood mononuclear cells (HumanRef-8)

Analysis of peripheral blood mononuclear cells from shoe factory workers exposed to benzene. Benzene is a leukemogen. Results provide insight into molecular mechanisms of benzene carcinogenicity.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL2700
Series:: GSE9569
16 Samples

Download data

DataSet

Accession:: GDS3561

ID:: 3561

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 35594.

Occupational benzene exposure: peripheral blood mononuclear cells (HG-U133A)

Analysis of peripheral blood mononuclear cells from shoe factory workers exposed to benzene. Benzene is a leukemogen. Results provide insight into molecular mechanisms of benzene carcinogenicity.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL96
Series:: GSE9569
16 Samples

Download data: CEL

DataSet

Accession:: GDS3559

ID:: 3559

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000218625.

Gene expression on 144 arrays representing 125 workers exposed to a range of benzene exposures

(Submitter supplied) Human toxicogenomic studies to date have been of limited size, have mainly addressed exposures at the upper end of typical ranges of human exposure, and have often lacked precise, individual estimates of exposure. Previously, we identified genes associated with exposure to high (>10 ppm) levels of the leukemogen, benzene, through transcriptomic analyses of blood cells from small numbers of occupationally exposed workers. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6104
144 Samples

Download data: TXT

Series

Accession:: GSE21862

ID:: 200021862

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Select item 2001195336.

nCounter analysis of mRNAs associated with occupational benzene exposure using a Nanostring custom assay

(Submitter supplied) Previously, using microarrays and mRNA-Sequencing (mRNA-Seq) we found that occupational exposure to a range of benzene levels perturbed gene expression in peripheral blood mononuclear cells. In the current study, we sought to identify gene expression biomarkers predictive of benzene exposure below 1 part per million (ppm), the occupational standard in the U.S. First, we used the nCounter platform to validate altered expression of 30 genes in 33 unexposed controls and 57 subjects exposed to benzene (<1 to ≥5 ppm). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL25533
96 Samples

Download data: XLSX

Series

Accession:: GSE119533

ID:: 200119533

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Select item 2000337607.

Transcriptomic analyis of the response of porcine PBMC to stimulation with concanavalin A

(Submitter supplied) One of the top priorities of the swine industry worldwide is to decrease the susceptibility of its animals to infectious diseases. There is therefore now an increased focus on the production of more “robust” animals, which have lower susceptibility to a broad range of infectious diseases. One general measure of immune competence is the proliferative response of peripheral blood mononuclear cells (PBMC) to mitogenic stimulation. more...

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL14897
24 Samples

Download data: GPR

Series

Accession:: GSE33760

ID:: 200033760

Select item 2000403928.

Gene expression of PBMC of chinese nickel refinery workers when compared to the gene expression profile of PBMCs from referent subjects

(Submitter supplied) Up to date the studies examining the gene expression profiles in response to exposure to nickel compounds have only been conducted using in vitro tissue culture systems. Here, we have compared the gene expression profiles in peripheral blood mononuclear cells (PMCs) of eight nickel refinery workers in Jinchang, China to the expression profiles of referent subjects with only environmental exposure.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4974
Platform:: GPL6244
18 Samples

Download data: CEL

Series

Accession:: GSE40392

ID:: 200040392

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Select item 49749.

High occupational exposure to nickel: peripheral blood mononuclear cell

Analysis of peripheral blood mononuclear cells from 8 nickel refinery workers. Occupational exposure to nickel is associated with an increased risk of lung and nasal cancers. Results provide insight into molecular mechanisms underlying nickel carcinogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 stress sets

Platform:: GPL6244
Series:: GSE40392
18 Samples

Download data: CEL

DataSet

Accession:: GDS4974

ID:: 4974

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20000614010.

Cross platform microarray analysis for robust identification of differentially expressed genes

(Submitter supplied) Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternative that is complementary to RT-PCR for identification of the more robust changes in gene expression profiles. In this paper, we combined statistical and functional analysis for the cross platform validation of two oligonucleotide-based technologies, Affymetrix (AFFX) and Applied Biosystems (ABI), and for the identification of differentially expressed genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL570 GPL1426
12 Samples

Download data: CEL

Series

Accession:: GSE6140

ID:: 200006140

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Select item 20000307711.

Dillution series comparison of Affymetrix and Illumina Expression Platforms

(Submitter supplied) The growth in popularity of RNA expression microarrays has been accompanied by concerns about the reliability of the data especially when comparing between different platforms. Here we present an evaluation of the reproducibility of microarray results using two platforms, Affymetrix GeneChips and Illumina BeadArrays. The study design is based on a dilution series of two human tissues (blood and placenta), tested in duplicate on each platform. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL570 GPL2725
24 Samples

Download data: CEL

Series

Accession:: GSE3077

ID:: 200003077

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Select item 20001154012.

Performance comparison of Affymetrix and Illumina microarray technologies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL6097 GPL570
20 Samples

Download data: CEL, TXT

Series

Accession:: GSE11540

ID:: 200011540

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Select item 20001143013.

Performance comparison of Affymetrix and Illumina microarray technologies_AffymetrixDataset

(Submitter supplied) The present study was conducted to compare the ability of Affymetrix and Illumina microarray technologies to characterize the differential gene expression profiles of human monocytes and monocyte-derived-macrophages. Keywords: Type Cross-platform comparison Summary

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3554
Platform:: GPL570
10 Samples

Download data: CEL

Series

Accession:: GSE11430

ID:: 200011430

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Select item 20001022014.

Gene expression profiling of human monocytes and monocyte-derived-macrophages

(Submitter supplied) In this study we analyzed the gene expression profiles of human monocytes and monocyte-dervied-macrophages. Keywords: Gene expression profiling

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3553
Platform:: GPL1946
96 Samples

Download data: GPR

Series

Accession:: GSE10220

ID:: 200010220

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Select item 20001021315.

Performance comparison of Affymetrix and Illumina microarray technologies_IlluminaDataSet

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3555
Platform:: GPL6097
10 Samples

Download data: TXT

Series

Accession:: GSE10213

ID:: 200010213

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Select item 355516.

Monocytes and macrophages (Illumina)

Comparison of monocytes and macrophages. Samples obtained from patients with acute coronary syndrome. Results compared to the performance of Affymetrix arrays (GDS3554). The result from two-color arrays (GDS3553) was used as a reference for the Illumina and Affymetrix arrays.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell type, 5 individual sets

Platform:: GPL6097
Series:: GSE10213
10 Samples

Download data: TXT

DataSet

Accession:: GDS3555

ID:: 3555

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 355417.

Monocytes and macrophages (Affymetrix)

Comparison of monocytes and macrophages. Samples obtained from patients with acute coronary syndrome. Results compared to the performance of Illumina arrays (GDS3555). The result from two-color arrays (GDS3553) was used as a reference for the Illumina and Affymetrix arrays.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell type, 5 individual sets

Platform:: GPL570
Series:: GSE11430
10 Samples

Download data: CEL

DataSet

Accession:: GDS3554

ID:: 3554

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 355318.

Monocytes and macrophages (RNG/MRC)

Comparison of monocytes and macrophages. Samples obtained from 86 patients with acute coronary syndrome. Results used as a reference to compare the performance of Affymetrix (GDS3554) and Illumina (GDS3555) arrays.

Organism:: Homo sapiens

Type:: Expression profiling by array, log ratio, 2 cell type, 48 individual, 2 protocol sets

Platform:: GPL1946
Series:: GSE10220
96 Samples

Download data: GPR

DataSet

Accession:: GDS3553

ID:: 3553

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20002266819.

Expression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence

(Submitter supplied) Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gene expression profiles leading to development of differnet diseases and disorders are not fully understood. The knowledge of global gene expression will help us to devlop early disease or disorder biomarkers for PCB induced health effects. We used microarrays to detail the global gene expression profile underlying the effects of mixed PCB exposure at Slovak Human equivalance Level on human PBMC leading to identification of distinct classes of up-regulated and down-regulated genes and cellular processes.