Similar studies for GEO DataSets (Select 4412) - GEO DataSets

Select item 44121.

Dietary fatty acid composition effect on vastus lateralis muscle

Analysis of skeletal muscle (SM) from insulin resistant men 4 hrs after consumption of meals high in saturated FA (SFA), monounsaturated FA (MUFA), or polyunsaturated FA (PUFA). Results provide insight into mechanisms underlying effects of FA composition on SM FA handling and insulin sensitivity.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 10 individual, 3 protocol, 2 time sets

Platform:: GPL6244
Series:: GSE31901
56 Samples

Download data: CEL

DataSet

Accession:: GDS4412

ID:: 4412

Select item 2000319012.

Polyunsaturated fatty acids acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increases postprandial insulin sensitivity

(Submitter supplied) Dietary fat quality may influence skeletal muscle lipid handling and fat accumulation, thereby modulating insulin sensitivity. Objective: To examine acute effects of meals with various fatty acid (FA) compositions on skeletal muscle FA handling and postprandial insulin sensitivity in obese insulin resistant men. Design: In a single-blinded randomized crossover study, 10 insulin resistant men consumed three high-fat mixed-meals (2.6MJ). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4412
Platform:: GPL6244
56 Samples

Download data: CEL

Series

Accession:: GSE31901

ID:: 200031901

Select item 2000134663.

Acute effects of different dietary fatty acids on the gene expression profiles of PBMCs of healthy young men

(Submitter supplied) Acute effects of different dietary fatty acids on the gene expression profiles of peripheral blood mononuclear cells in healthy young men. A randomized cross-over study. Gene expression profiles of peripheral blood mononuclear cells (PBMCs) have been used to reflect pathological and physiological states of humans. We theorized that these cells could also be used to show fatty acid specific gene expression profiles. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3704
Platform:: GPL7144
84 Samples

Download data: CEL

Series

Accession:: GSE13466

ID:: 200013466

Select item 37044.

Dietary polyunsaturated and saturated fatty acids effect on peripheral blood mononuclear cells

Analysis of peripheral blood mononuclear cells of individuals before and 6 hours after the consumption of shakes containing either mainly polyunsanturated (PUFA) or saturated fatty acids (SFA). Results provide insight into the molecular basis of the beneficial effect of PUFA on health.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 42 individual, 2 protocol sets

Platform:: GPL7144
Series:: GSE13466
84 Samples

Download data: CEL

DataSet

Accession:: GDS3704

ID:: 3704

Select item 2000385905.

Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels

(Submitter supplied) Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid storage exceeds intracellular needs and induces lipotoxic events ultimately contributing to the development of insulin resistance. Lipid droplet (LD)-coating proteins may control proper lipid storage in skeletal muscle. Perilipin 2 (PLIN2/ADRP) is one of the most abundantly expressed LD-coating proteins in skeletal muscle. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
6 Samples

Download data: CEL

Series

Accession:: GSE38590

ID:: 200038590

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000716146.

Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial

(Submitter supplied) The obese, insulin resistant state is characterized by impairments in lipid metabolism. Dietary polyphenols might improve these deteriorations. We have previously shown that 3-days supplementation of combined Epigallocatechin-gallate and Resveratrol (E+R) increased energy expenditure, which was accompanied by improved metabolic flexibility after a high-fat mixed-meal (HFMM) in men. The present study aimed to investigate whether these short-term effects translate into longer-term improvement of insulin sensitivity and lipid metabolism. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
54 Samples

Download data: CEL

Series

Accession:: GSE71614

ID:: 200071614

Select item 2001068007.

Circadian misalignment induces fatty acid metabolism gene profiles and induces insulin resistance in human skeletal muscle.

(Submitter supplied) Circadian misalignment, such as in shift work, has been associated with obesity and type 2 diabetes, however, direct effects of circadian misalignment on skeletal muscle insulin sensitivity and muscle molecular circadian clock have never been investigated in humans. Here we investigated insulin sensitivity and muscle metabolism in fourteen healthy young lean men (age 22.4 ± 2.8 years; BMI 22.3 ± 2.1 kg/m2 [mean ± SD]) after a 3-day control protocol and a 3.5-day misalignment protocol induced by a 12-h rapid shift of the behavioral cycle. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17692
47 Samples

Download data: CEL

Series

Accession:: GSE106800

ID:: 200106800

PubMed Full text in PMC Similar studies Analyze with GEO2R

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