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Full record GDS4802

WTX overexpression effect on kidney cell line

Analysis of HEK293 embryonic kidney cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Ectopic expression of WTX in HEK293 cells activates p53 through lysine acetylation. Results provide insight into a role for WTX in the regulation of p53 activity.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL570
Series:
GSE34715
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4802
ID:
4802

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