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Full record GDS4826

ARID1A depletion effect on ovarian surface epithelial cell lines

Analysis of OSE4 and IOSE80pc ovarian surface epithelial cells depleted for ARID1A, which encodes large nuclear protein p270. ARID1A depletion enhances OSE4 and IOSE80pc proliferation. OSE4 cells become highly tumorigenic upon ARID1A depletion. Results suggest a tumor-suppressor role for ARID1A.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell line, 2 protocol sets
Platform:
GPL10558
Series:
GSE37684
4 Samples
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