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Full record GDS5620

H3K79 histone methyl transferase DOT1L inhibitor Compound 55 effect on breast cancer cells: dose response

Analysis of MDA-MB-231 breast cancer cells treated with DOT1L (disruptor of telomeric silencing 1 like) inhibitor Compound 55 or DOT1L siRNA. DOT1L is a histone H3-lysine79 (H3K79) methyltransferase. Results provide insight into the role of DOT1L/H3K79 methylation in breast cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 agent, 4 dose sets
Platform:
GPL10558
Series:
GSE56630
8 Samples
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DataSet
Accession:
GDS5620
ID:
5620

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