Methyl-CpG-binding protein 2 binding disruption during neuronal maturation - - GEO DataSets

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Methyl-CpG-binding protein 2 binding disruption during neuronal maturation

Analysis of SH-SY5Y cells undergoing PMA-induced neuronal maturational differentiation after transfection with a MeCP2 decoy to disrupt binding of MeCP2 to endogenous targets. Results provide insight into the pathogenesis of Rett syndrome, a neurodevelopmental disorder caused by mutations in MeCP2.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 cell type, 3 protocol sets

Platform:: GPL570
Series:: GSE4600
12 Samples

Download data: CEL

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Accession:: GDS2125

ID:: 2125

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