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Full record GDS2125

Methyl-CpG-binding protein 2 binding disruption during neuronal maturation

Analysis of SH-SY5Y cells undergoing PMA-induced neuronal maturational differentiation after transfection with a MeCP2 decoy to disrupt binding of MeCP2 to endogenous targets. Results provide insight into the pathogenesis of Rett syndrome, a neurodevelopmental disorder caused by mutations in MeCP2.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 cell type, 3 protocol sets
Platform:
GPL570
Series:
GSE4600
12 Samples
Download data: CEL

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