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Full record GDS4083

Lapatinib-resistant HER2-positive breast tumor cells

Analysis of BT474 (lapatinib-sensitive) and BT474-J4 (acquired lapatinib-resistance) HER2+ breast cancer cells treated with lapatinib, foretinib or both. Foretinib restored lapatinib-sensitivity in BT474-J4. Results provide insight into molecular basis of acquired lapatinib-resistance in BC cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 2 cell line, 2 genotype/variation sets
Platform:
GPL570
Series:
GSE16179
18 Samples
Download data: CEL
DataSet
Accession:
GDS4083
ID:
4083

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