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Full record GDS4175

Imatinib effect on Philadelphia chromosome positive acute lymphoblastic leukemia cells

Analysis of Ph+ ALL cell lines (BV-173, NALM-1, SUP-B15, and TOM1) treated with tyrosine kinase inhibitor (TKI) imatinib. Ph encodes oncogenic BCR-ABL1 tyrosine kinase, which defines a subset of ALL with an unfavorable prognosis. Results provide insight into TKI resistance mechanisms in Ph+ ALL.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 4 cell line sets
Platform:
GPL571
Series:
GSE23743
8 Samples
Download data: CEL

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