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Full record GDS4383

Saracatinib-sensitive versus -resistant, PIK3CA mutant colorectal cancer xenografts

Analysis of patient-derived colorectal cancer (CRC) xenografts with a PIK3CA mutation with enhanced sensitivity to Src inhibitor saracatinib. Dysregulation of Src and PI3K (phosphoinositide 3-kinase) signaling pathways is common in CRC. Results provide insight into CRC model response to saracatinib.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL6244
Series:
GSE36006
4 Samples
Download data: CEL
DataSet
Accession:
GDS4383
ID:
4383

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