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Full record GDS4291

Inhibition of Notch signaling in T cell acute lymphoblastic leukemia cell lines

Analysis of T-ALL cell lines treated with γ-secretase inhibitor (GSI) to block Notch signaling. Cell lines include parental cells and cells transduced with ICN (a GSI-independent form of activated Notch1) or with c-Myc (a downstream Notch1 target). Results provide insight into Notch1 role in T-ALL.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 5 cell line, 3 genotype/variation sets
Platform:
GPL570
Series:
GSE29959
30 Samples
Download data: CEL

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