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Full record GDS4306

DNA methyltransferase Dnmt1 knockout effect on leukemia stem cells and bulk leukemia cells

Analysis of Dnmt1 haploinsufficient leukemia stem cells (leukemic granulocytemacrophage progenitors; L-GMPs) and bulk leukemia cells from a model of MLL-AF9-induced acute myeloid leukemia (AML). Dnmt1 haploinsufficiency delays progression of AML. Results provide insight into role of Dnmt1 in AML.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 2 genotype/variation sets
Platform:
GPL8321
Series:
GSE31626
8 Samples
Download data: CEL

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