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Full record GDS4507

Endoplasmic reticulum thiol oxidase deficiency effect on embryonic fibroblasts

Analysis of MEFs deficient in ER thiol oxidases (ERO1a, ERO1b) and PRDX4, enzymes that initiate the disulfide relay. Combined loss-of-function mutations compromise the extracellular matrix and interfere with procollagen maturation. Results provide insight into the molecular basis of these defects.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation sets
Platform:
GPL6246
Series:
GSE39492
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4507
ID:
4507

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