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Full record GDS4188

CD3+ T cell response to stimulation with CD3/CD28 or nitric oxide

Analysis of healthy T cells stimulated with CD3/CD28 (a Ca2+ fluxing inducer) or NO (a key trigger of mitochondrial hyperpolarization (MHP)). Enhanced Ca2+ fluxing and MHP underlie aberrant T-cell activation in SLE. Results provide insight into the molecular basis of T cell dysfunction in lupus.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent sets
Platform:
GPL570
Series:
GSE13887
12 Samples
Download data: CEL, CHP

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