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Full record GDS4539

TRIF-deficient Herpes simplex encephalitis patient: fibroblast response to interleukin-1β and TLR3 agonist poly (I:C)

Analysis of SV40 skin fibroblasts collected from an HSV1 encephalitis (HSE) patient with TRIF deficiency (homozygous TRIF nonsense mutation) and stimulated with IL-1β or poly I:C . TRIF is the sole adaptor protein for TLR3. Results provide insight into the role of the TLR3 pathway in HSE.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 agent, 2 disease state, 4 genotype/variation sets
Platform:
GPL10558
Series:
GSE32390
18 Samples
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DataSet
Accession:
GDS4539
ID:
4539

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