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Full record GDS4544

G-protein-coupled receptor kinase 2 inhibition effect on HEK cells in vitro and in vivo

Analysis of HEK cells expressing dominant-negative GRK2-K220R. HEK cells were cultured, or expanded in NOD.Scid mice, or re-cultured after NOD.Scid expansion. GRK2-K220R enhances growth of NOD.Scid HEK cells but not cultured HEK cells. Results provide insight into basis of growth control by GRK2.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 genotype/variation, 3 protocol sets
Platform:
GPL570
Series:
GSE42771
12 Samples
Download data: CEL, CHP

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