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Rapid protection induced by a single-shot Lassa vaccine in cynomolgus monkeys

(Submitter supplied) Lassa fever outbreaks hit West African countries every year and there is still no licensed vaccine to limit the burden of this viral hemorrhagic fever. We previously developed MeV-NP, a single-shot vaccine that induces protective immunity in cynomolgus monkeys one month or more than a year before Lassa virus infection and that is able to protect against divergent viral strains. Given the limited dissemination area of Lassa virus during outbreaks and the high risk of nosocomial transmission, a vaccine that induces rapid protection could be useful to protect exposed people during outbreaks in the absence of preventive vaccination. more...
Organism:
Macaca fascicularis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22523
51 Samples
Download data: CSV
Series
Accession:
GSE225258
ID:
200225258

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