A genome wide role for CHD remodeling factors and Nap1 in nucleosome disassembly - - GEO DataSets

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A genome wide role for CHD remodeling factors and Nap1 in nucleosome disassembly

(Submitter supplied) Chromatin remodeling factors and histone chaperones were previously shown to cooperatively affect nucleosome assembly and disassembly processes in vitro. Here we show that S. pombe CHD remodellers, Hrp1 and Hrp3 physically interact with the histone chaperone Nap1. Genome wide analysis of Hrp1, Hrp3 and Nap1 occupancy, combined with nucleosome density measurements in respective mutants revealed that the CHD factors and Nap1 co-localized in particular to promoter regions where they remove nucleosomes near the transcriptional start site. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by array; Genome binding/occupancy profiling by genome tiling array

9 related Platforms
54 Samples

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Accession:: GSE6557

ID:: 200006557

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