GEO DataSet Links for PMC (Select 2176127) - GEO DataSets

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Items: 2

Select item 2000074751.

Inflammatory response to titanium dioxide particles exposure is enhanced during pregnancy

(Submitter supplied) Rationale: Maternal immune responses can promote allergy development in offspring. Pilot data show that neonates of mother mice exposed during pregnancy to air pollution particles have increased allergic susceptibility. Objective: We investigated whether inflammatory response to titanium dioxide (TiO2) particles earlier considered immunologically ‘inert’ is enhanced during pregnancy. Methods: Pregnant BALB/c mice (or non-pregnant controls) received particle suspensions intranasally at day 14 of pregnancy. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2878
Platform:: GPL1261
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE7475

ID:: 200007475

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28782.

Inert particles effect on the lungs of pregnant females

Analysis of lungs from pregnant and non-pregnant BALB/c females following insufflation with inert titanium dioxide particles. Results provide insight into the mechanisms underlying the differences in response between pregnant and non-pregnant females to inhaled inert particles.